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- W2317961872 abstract "We investigated 21 cutaneous lesions of leprosy in several clinical stages, using antihuman T, B lymphocytes sera, acid a- naphthyl acetate esterase stain and anti-human T lymphocytes monoclonal antibodies.We found the difference in lymphocyte subpopulation between inflammatory infiltrates in active and inactive lesions of lepromatous leprosy.The mononuclear cell infiltrates in active lesions were composed mainly of T lymphocytes, and spare perivascular infiltrates in inactive lesions were mainly of B lymphocytes. Particularly, the infiltrates in active lesions were composed predominantly of OKT-8 (suppressor/cytotoxic T) positive cells, in addition, it also contained a small number of OKT-4 (helper/inducer T) positive cells. It is not clear that either suppressor or cytotoxic T cells infiltrated around leproma.These findings suggest lymphocyte infiltrates concerned with immunological tolerance in lepromatous leprosy." @default.
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- W2317961872 date "1983-01-01" @default.
- W2317961872 modified "2023-09-26" @default.
- W2317961872 title "Identification of Lymphocyte Subpopulation in Cutaneous Lesions of Leprosy" @default.
- W2317961872 doi "https://doi.org/10.5025/hansen1977.52.126" @default.
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