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- W2318056876 abstract "An antibiotic formycin A inhibited growth of Vibrio parahaemolyticus under certain conditions, which suggested that formycin A was taken up by cells under these conditions. We found that formycin A was transported via the adenosine transport system which we previously reported as a Na(+)-coupled cotransport system. We isolated many formycin A resistant mutants, and about half of them grew very poorly on adenosine as a sole source of carbon. Judging from their reversion frequencies, these mutants seemed to have single mutations. Respiration driven uptake of 14C-adenosine was not observed in such mutants; also, Na+ uptake induced by the addition of adenosine or formycin A to a cell suspension was completely abolished in them. Thus we conclude that these mutants possess a defect in the Na+/adenosine cotransport system, and have become formycin A resistant." @default.
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- W2318056876 date "1991-01-01" @default.
- W2318056876 modified "2023-09-26" @default.
- W2318056876 title "Formycin A Resistant Mutants Due to Defect in Adenosine Transport System in Vibrio parahaemolyticus." @default.
- W2318056876 doi "https://doi.org/10.1248/cpb.39.1325" @default.
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