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- W2318079341 endingPage "4259" @default.
- W2318079341 startingPage "4252" @default.
- W2318079341 abstract "Significance Human blood provides a rich source of information about metabolites that reflects individual differences in health, disease, diet, and lifestyle. The coefficient of variation for human blood metabolites enriched in red blood cells or plasma was quantified after careful preparation. We identified 14 age-related metabolites. Metabolites that decline strikingly in the elderly include antioxidants and compounds involved in high physical activity, including carnosine, UDP-acetyl-glucosamine, ophthalmic acid,1,5-anhydroglucitol, NAD + , and leucine. Metabolites that increase significantly in the elderly include compounds related to declining renal and liver function. Statistical analysis suggests that certain age-related compounds that either increased or decreased in the elderly are correlated. Individual variability in blood metabolites may lead to identify candidates for markers of human aging or relevant diseases." @default.
- W2318079341 created "2016-06-24" @default.
- W2318079341 creator A5004377531 @default.
- W2318079341 creator A5056671880 @default.
- W2318079341 creator A5069492607 @default.
- W2318079341 creator A5084455127 @default.
- W2318079341 creator A5091007752 @default.
- W2318079341 date "2016-03-28" @default.
- W2318079341 modified "2023-10-17" @default.
- W2318079341 title "Individual variability in human blood metabolites identifies age-related differences" @default.
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- W2318079341 doi "https://doi.org/10.1073/pnas.1603023113" @default.