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- W2318095130 abstract "Background Acute aortic dissection (AAD) is a highly lethal medical emergency that requires immediate assessment and therapy. To date, no one biomarker plays a significant role in risk stratification of patients with AAD and whether cardiac troponin could be a prognostic marker of in-hospital mortality is still unknown. Methods and results To assess the prognostic role of cardiac troponin elevation during AAD, we performed an updated systematic review and meta-analysis. Four studies were included in the final analysis. Elevated cardiac troponin was present in 26.8% of patients with AAD and ranged between 23% and 33%. We showed that elevated troponin levels were significantly associated with increased risk of short-term mortality (OR 2.57; 95% CI 1.66–3.96). The analysis of pooled studies showed a low heterogeneity (I2 34.3%), and no publication bias was detected (Egger bias 3.34, p = 0.18). Conclusions Cardiac troponin elevation at the time of admission for AAD is associated with an increased risk of in-hospital mortality." @default.
- W2318095130 created "2016-06-24" @default.
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- W2318095130 date "2016-07-01" @default.
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- W2318095130 title "Prognostic effect of cardiac troponin elevation in acute aortic dissection: A meta-analysis" @default.
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- W2318095130 doi "https://doi.org/10.1016/j.ijcard.2016.03.230" @default.
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