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• W2318160820 abstract "You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Male Incontinence: Therapy II1 Apr 2016PD49-02 MAGNETIC ARTIFICIAL SPHINCTER (MARS): A NOVEL URINARY SPHINCTER FOR STRESS URINARY INCONTINENCE Navneet Mander, Mahdi Mohammadi, Mohsen Shahinpoor, Krishna Bhatta, and Nivedita Dhar Navneet ManderNavneet Mander More articles by this author , Mahdi MohammadiMahdi Mohammadi More articles by this author , Mohsen ShahinpoorMohsen Shahinpoor More articles by this author , Krishna BhattaKrishna Bhatta More articles by this author , and Nivedita DharNivedita Dhar More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.2738AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES We present a prototype artificial urinary sphincter that was developed and put through simulation testing to provide a competent bladder outlet during urinary storage and an open, unobstructed outlet to permit voluntary voiding. METHODS The MARS prototype utilizes a control unit in the scrotum housing an internal magnet (IM) with axial movement controlled by placement of an external magnet (EM) to ultimately control the circumference of a urethral compression cuff (UCC) and, as a result, the urethral outflow resistance (fig. 1). At baseline, IM is held in open position secondary to its intrinsic attractive magnetic force to the metal base plate. Placing an EM creates a larger opposing force to overcome the attractive force allowing movement of IM into open position. The UCC was placed around a simulated urethra connected to a fluid reservoir to model intra-vesicular pressure during urination and stress/exertion. Analytical and finite element analysis utilizing the COMSOL Multiphysics simulation software and experimental analysis was used to calculate opening, closing, and holding forces. An x-ray of the device was taken in the open and closed position (Fig. 2). RESULTS The prototype was cycled 50 times with successful continence at 60 cm of water and complete emptying in every trial. The calculated opening force was 1.6 N, holding force was 1.1 N, and closing force ranged from 0.4 N to 3.8 N. The important factors that determined the forces on the internal magnet and, consequently, the external sphincter pressure are gap 1, gap 2, and strength of external and internal magnets. CONCLUSIONS Potential advantages of this novel device over current technology include a less invasive surgical implantation (no reservoir), less reliance on patient manual dexterity, improvement in mechanical failure rate secondary to a decrease in the number of components, and ability of x-ray to readily determine open versus closed position of the cuff. Further animal testing is being pursued to assess biocompatibility and efficacy ex vivo and in vitro. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e1180-e1181 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Navneet Mander More articles by this author Mahdi Mohammadi More articles by this author Mohsen Shahinpoor More articles by this author Krishna Bhatta More articles by this author Nivedita Dhar More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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• W2318160820 title "PD49-02 MAGNETIC ARTIFICIAL SPHINCTER (MARS): A NOVEL URINARY SPHINCTER FOR STRESS URINARY INCONTINENCE" @default.
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