FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2318184906> ?p ?o ?g. }

• W2318184906 endingPage "11447" @default.
• W2318184906 startingPage "11433" @default.
• W2318184906 abstract "NMR experiments have shown that water molecules in the crystal of the protein Crh are still mobile at temperatures well below 273 K. In order to investigate this water anomaly, a molecular dynamics (MD) simulation study of crystalline Crh was carried out to determine the mobility of water in this crystal. The simulations were carried out at three temperatures, 150, 200, and 291 K. Simulations of bulk water at these temperatures were also done to obtain the properties of the simple point charge (SPC) water model used at these temperatures and to allow a comparison of the properties of water in the Crh crystal with those of bulk water at the same temperatures. According to the simulations, water is immobilized at 150 K both in crystal and in bulk water. As expected, at 291 K it diffuses and rotates more slowly in the protein crystal than in bulk water. However, at 200 K, the translational and rotational mobility of the water molecules is larger in the crystal than in bulk water. The enhancement of water mobility in the crystal at 200 K was further investigated by MD simulations in which the backbone or all protein atoms were positionally restrained, and in which additionally the electrostatic protein-water interactions were removed. Of these changes in the environment of the water molecules, rigidifying the protein backbones slightly enhanced water diffusion, while it slowed down rotation. In contrast, removal of electrostatic protein–water interactions did not change water diffusion but enhanced rotational motion significantly. Further investigations are required to delineate particular features of the protein crystal that induce the anomalous behavior of water at 200 K." @default.
• W2318184906 created "2016-06-24" @default.
• W2318184906 creator A5001436183 @default.
• W2318184906 creator A5004707292 @default.
• W2318184906 creator A5063856246 @default.
• W2318184906 creator A5076009010 @default.
• W2318184906 creator A5086386273 @default.
• W2318184906 date "2013-09-23" @default.
• W2318184906 modified "2023-09-26" @default.
• W2318184906 title "On the Behavior of Water at Subfreezing Temperatures in a Protein Crystal: Evidence of Higher Mobility Than in Bulk Water" @default.
• W2318184906 cites W1491824558 @default.
• W2318184906 cites W1518327983 @default.
• W2318184906 cites W154742896 @default.
• W2318184906 cites W1986242879 @default.
• W2318184906 cites W1986982278 @default.
• W2318184906 cites W1990677639 @default.
• W2318184906 cites W1991775910 @default.
• W2318184906 cites W1992601431 @default.
• W2318184906 cites W1997733557 @default.
• W2318184906 cites W2006152156 @default.
• W2318184906 cites W2007696963 @default.
• W2318184906 cites W2008708467 @default.
• W2318184906 cites W2010260586 @default.
• W2318184906 cites W2014694459 @default.
• W2318184906 cites W2017417570 @default.
• W2318184906 cites W2020546548 @default.
• W2318184906 cites W2027053193 @default.
• W2318184906 cites W2027154929 @default.
• W2318184906 cites W2031107710 @default.
• W2318184906 cites W2032456809 @default.
• W2318184906 cites W2033906450 @default.
• W2318184906 cites W2035266068 @default.
• W2318184906 cites W2035334234 @default.
• W2318184906 cites W2040389523 @default.
• W2318184906 cites W2049155925 @default.
• W2318184906 cites W2049475242 @default.
• W2318184906 cites W2049747350 @default.
• W2318184906 cites W2051326312 @default.
• W2318184906 cites W2052466177 @default.
• W2318184906 cites W2053140944 @default.
• W2318184906 cites W2053731362 @default.
• W2318184906 cites W2055341112 @default.
• W2318184906 cites W2058955158 @default.
• W2318184906 cites W2060189458 @default.
• W2318184906 cites W2061612744 @default.
• W2318184906 cites W2063379618 @default.
• W2318184906 cites W2067228077 @default.
• W2318184906 cites W2068818545 @default.
• W2318184906 cites W2069660906 @default.
• W2318184906 cites W2074684502 @default.
• W2318184906 cites W2075092972 @default.
• W2318184906 cites W2075770210 @default.
• W2318184906 cites W2076036860 @default.
• W2318184906 cites W2078493190 @default.
• W2318184906 cites W2082750654 @default.
• W2318184906 cites W2087596773 @default.
• W2318184906 cites W2089669941 @default.
• W2318184906 cites W2090564140 @default.
• W2318184906 cites W2090667060 @default.
• W2318184906 cites W2091416241 @default.
• W2318184906 cites W2092735708 @default.
• W2318184906 cites W2093185451 @default.
• W2318184906 cites W2093221728 @default.
• W2318184906 cites W2094358723 @default.
• W2318184906 cites W2106140689 @default.
• W2318184906 cites W2106466007 @default.
• W2318184906 cites W2113149246 @default.
• W2318184906 cites W2115407883 @default.
• W2318184906 cites W2124691604 @default.
• W2318184906 cites W2125938217 @default.
• W2318184906 cites W2142428599 @default.
• W2318184906 cites W2146614850 @default.
• W2318184906 cites W2155153626 @default.
• W2318184906 cites W2155858732 @default.
• W2318184906 cites W2162287162 @default.
• W2318184906 cites W2163440447 @default.
• W2318184906 cites W2164442956 @default.
• W2318184906 cites W2168679437 @default.
• W2318184906 cites W2169085096 @default.
• W2318184906 cites W2333752828 @default.
• W2318184906 cites W2950212660 @default.
• W2318184906 cites W3101217599 @default.
• W2318184906 doi "https://doi.org/10.1021/jp400655v" @default.
• W2318184906 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23998392" @default.
• W2318184906 hasPublicationYear "2013" @default.
• W2318184906 type Work @default.
• W2318184906 sameAs 2318184906 @default.
• W2318184906 citedByCount "0" @default.
• W2318184906 crossrefType "journal-article" @default.
• W2318184906 hasAuthorship W2318184906A5001436183 @default.
• W2318184906 hasAuthorship W2318184906A5004707292 @default.
• W2318184906 hasAuthorship W2318184906A5063856246 @default.
• W2318184906 hasAuthorship W2318184906A5076009010 @default.
• W2318184906 hasAuthorship W2318184906A5086386273 @default.
• W2318184906 hasConcept C113196181 @default.
• W2318184906 hasConcept C119049451 @default.
• W2318184906 hasConcept C121332964 @default.
• W2318184906 hasConcept C147597530 @default.

• next