Matches in SemOpenAlex for { <https://semopenalex.org/work/W2318202318> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2318202318 endingPage "418" @default.
- W2318202318 startingPage "411" @default.
- W2318202318 abstract "1) In isolated perfused rat liver, the intracellular ([14C]urea-accessible minus [3H]inulin accessible) water space was determined from the washout profiles of simultaneously infused [3H]inulin and [14C]urea. The washout profile of infused [14C]urea was indistinguishable from that of infused tritiated water. During normotonic perfusions and without hormones or amino acids in influent, the intracellular water space was 548 +/- 10 microliters/g liver wet weight (n = 44). Use of [3H]raffinose instead of [3H]inulin as marker for the extracellular space yielded almost identical values for the intracellular water space (i.e. 98.9 +/- 0.2% of that found with [3H]inulin/[14C]urea). When volume-regulatory K+ fluxes were completed following hypo- and hypertonic exposure of perfused rat livers and a steady state was reached, the intracellular water space was found to be increased and decreased, respectively. The extent of anisotonic exposure was linearly related to the change of intracellular water space. 2) Anisotonicity-, glutamine- and glycine-induced liver mass changes were almost fully explained by the simultaneously occurring alterations of the intracellular water space, indicating that cell volume changes in perfused rat liver under these conditions are not accompanied by significant changes of the extracellular space. Volume-regulatory K+ (plus accompanying anion) efflux following hypotonic perfusion accounted for about 70-85% of regulatory cell volume decrease, which occurred during the first 10 min of hypotonic exposure. 3) Cell volume of isolated hepatocytes was determined as the hepatocrit after gentle centrifugation of the cell suspension.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
- W2318202318 created "2016-06-24" @default.
- W2318202318 creator A5008452332 @default.
- W2318202318 creator A5020374449 @default.
- W2318202318 creator A5035270139 @default.
- W2318202318 creator A5071180693 @default.
- W2318202318 creator A5084208566 @default.
- W2318202318 date "1991-01-01" @default.
- W2318202318 modified "2023-09-26" @default.
- W2318202318 title "A Non-Invasive Technique for Cell Volume Determination in Perfused Rat Liver" @default.
- W2318202318 cites W1516463671 @default.
- W2318202318 cites W1814062958 @default.
- W2318202318 cites W2013707613 @default.
- W2318202318 cites W2039994054 @default.
- W2318202318 cites W2158561731 @default.
- W2318202318 doi "https://doi.org/10.1515/bchm3.1991.372.1.411" @default.
- W2318202318 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1910579" @default.
- W2318202318 hasPublicationYear "1991" @default.
- W2318202318 type Work @default.
- W2318202318 sameAs 2318202318 @default.
- W2318202318 citedByCount "44" @default.
- W2318202318 countsByYear W23182023182013 @default.
- W2318202318 countsByYear W23182023182014 @default.
- W2318202318 countsByYear W23182023182018 @default.
- W2318202318 crossrefType "journal-article" @default.
- W2318202318 hasAuthorship W2318202318A5008452332 @default.
- W2318202318 hasAuthorship W2318202318A5020374449 @default.
- W2318202318 hasAuthorship W2318202318A5035270139 @default.
- W2318202318 hasAuthorship W2318202318A5071180693 @default.
- W2318202318 hasAuthorship W2318202318A5084208566 @default.
- W2318202318 hasConcept C117277713 @default.
- W2318202318 hasConcept C126322002 @default.
- W2318202318 hasConcept C134018914 @default.
- W2318202318 hasConcept C185592680 @default.
- W2318202318 hasConcept C2113261 @default.
- W2318202318 hasConcept C2779742124 @default.
- W2318202318 hasConcept C2780365088 @default.
- W2318202318 hasConcept C28406088 @default.
- W2318202318 hasConcept C2992672570 @default.
- W2318202318 hasConcept C43617362 @default.
- W2318202318 hasConcept C55493867 @default.
- W2318202318 hasConcept C71924100 @default.
- W2318202318 hasConcept C79879829 @default.
- W2318202318 hasConcept C86803240 @default.
- W2318202318 hasConceptScore W2318202318C117277713 @default.
- W2318202318 hasConceptScore W2318202318C126322002 @default.
- W2318202318 hasConceptScore W2318202318C134018914 @default.
- W2318202318 hasConceptScore W2318202318C185592680 @default.
- W2318202318 hasConceptScore W2318202318C2113261 @default.
- W2318202318 hasConceptScore W2318202318C2779742124 @default.
- W2318202318 hasConceptScore W2318202318C2780365088 @default.
- W2318202318 hasConceptScore W2318202318C28406088 @default.
- W2318202318 hasConceptScore W2318202318C2992672570 @default.
- W2318202318 hasConceptScore W2318202318C43617362 @default.
- W2318202318 hasConceptScore W2318202318C55493867 @default.
- W2318202318 hasConceptScore W2318202318C71924100 @default.
- W2318202318 hasConceptScore W2318202318C79879829 @default.
- W2318202318 hasConceptScore W2318202318C86803240 @default.
- W2318202318 hasIssue "1" @default.
- W2318202318 hasLocation W23182023181 @default.
- W2318202318 hasLocation W23182023182 @default.
- W2318202318 hasOpenAccess W2318202318 @default.
- W2318202318 hasPrimaryLocation W23182023181 @default.
- W2318202318 hasRelatedWork W1569013596 @default.
- W2318202318 hasRelatedWork W1847346954 @default.
- W2318202318 hasRelatedWork W2001900930 @default.
- W2318202318 hasRelatedWork W2052293737 @default.
- W2318202318 hasRelatedWork W2052302929 @default.
- W2318202318 hasRelatedWork W2089932891 @default.
- W2318202318 hasRelatedWork W2317292539 @default.
- W2318202318 hasRelatedWork W2318202318 @default.
- W2318202318 hasRelatedWork W2336630253 @default.
- W2318202318 hasRelatedWork W2395748451 @default.
- W2318202318 hasVolume "372" @default.
- W2318202318 isParatext "false" @default.
- W2318202318 isRetracted "false" @default.
- W2318202318 magId "2318202318" @default.
- W2318202318 workType "article" @default.