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- W2318266629 abstract "To estimate the arylesterase activity of serum paraoxonase-1 (PON1-ARE), which is reported to have an antioxidant and antiatherogenic potential and to correlate with plasma homocysteine (Hcys) and plasma TBARS in young adult central retinal venous occlusion (CRVO) patients. A case–control prospective study carried out in 10 CRVO patients (mean age 27±5 years; 7 males, 3 females) and 20 healthy controls (mean age 29±5 years; 15 males, 5 females). The CRVO patients showed a significantly lowered serum PON1-ARE activity (P=0.009) along with a significant increase in the levels of plasma Hcys (P=0.018) when compared to the control subjects. There was a negative correlation between serum PON1-ARE and plasma Hcys levels (P=0.058) as well as between PON1-ARE and plasma TBARS levels (P=0.001) in the CRVO patients. This is the first report of lowered serum PON1-ARE level as a risk factor for CRVO (OR= 1.108, CI=0.914, 1.314; P=0.296), which is found to correlate with oxidative stress." @default.
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- W2318266629 date "2007-12-14" @default.
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- W2318266629 title "Serum PON1 arylesterase activity in relation to hyperhomocysteinaemia and oxidative stress in young adult central retinal venous occlusion patients" @default.
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- W2318266629 doi "https://doi.org/10.1038/sj.eye.6703062" @default.
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