Matches in SemOpenAlex for { <https://semopenalex.org/work/W2318380815> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2318380815 endingPage "233" @default.
- W2318380815 startingPage "230" @default.
- W2318380815 abstract "Abstract Aim To investigate antitumor compounds from Vernonia bockiana. Methods The compounds were isolated by column chromatography and preparative HPLC. Their structures were elucidated by 1 H and 13 C NMR spectroscopic methods and MS experiments. The antitumor activity was evaluated by testing their cytotoxicity against the human promyelomonocyte leukemic cell line HL-60 by the MTT method. Results Six sesquiterpene lactones, 8α-(4-hydroxymethacryloyloxy)-10α-hydroxy-13-methoxyhirsutinolide ( 1 ), 8α-methacryloyloxy-10α-hydroxy-13- O -methylhirsutinolide ( 2 ), piptocarphin A ( 3 ), 8α-[4-hydroxymethacryloyloxy]-10α-hydroxyhisutinolide-13- O -acetate ( 4 ), piptocarphin F ( 5 ), and 8α-acetoxy-10α-hydroxy-13- O -methylhirsutinolide ( 6 ), and one known inone glycoside, saussureosides B ( 7 ), were isolated from the whole plant of V . bockiana . The six sesquiterpene lactones showed cytotoxic activity (IC 50 3.87–12.5 μmol·L −1 ) against the human leukemic cell line HL-60 while the inone glycoside 7 was inactive in the test. Conclusion Compounds 1, 2, 6 , and 7 were obtained for the first time from this plant; The sesquiterpene lactones present in V . bockiana were active as antitumor agents against the human leukemic cell line HL-60." @default.
- W2318380815 created "2016-06-24" @default.
- W2318380815 creator A5005292574 @default.
- W2318380815 creator A5012677271 @default.
- W2318380815 creator A5058123246 @default.
- W2318380815 creator A5060002817 @default.
- W2318380815 creator A5065058975 @default.
- W2318380815 creator A5066591741 @default.
- W2318380815 creator A5076959779 @default.
- W2318380815 creator A5078526337 @default.
- W2318380815 date "2012-09-05" @default.
- W2318380815 modified "2023-09-27" @default.
- W2318380815 title "Cytotoxic sesquiterpene lactones from <I>Vernonia bockiana</I>" @default.
- W2318380815 cites W2013617890 @default.
- W2318380815 cites W2049851094 @default.
- W2318380815 cites W2149483159 @default.
- W2318380815 cites W2949472042 @default.
- W2318380815 cites W2952295575 @default.
- W2318380815 doi "https://doi.org/10.3724/sp.j.1009.2012.00230" @default.
- W2318380815 hasPublicationYear "2012" @default.
- W2318380815 type Work @default.
- W2318380815 sameAs 2318380815 @default.
- W2318380815 citedByCount "14" @default.
- W2318380815 countsByYear W23183808152013 @default.
- W2318380815 countsByYear W23183808152014 @default.
- W2318380815 countsByYear W23183808152015 @default.
- W2318380815 countsByYear W23183808152016 @default.
- W2318380815 countsByYear W23183808152017 @default.
- W2318380815 countsByYear W23183808152018 @default.
- W2318380815 countsByYear W23183808152019 @default.
- W2318380815 countsByYear W23183808152020 @default.
- W2318380815 countsByYear W23183808152021 @default.
- W2318380815 countsByYear W23183808152023 @default.
- W2318380815 crossrefType "journal-article" @default.
- W2318380815 hasAuthorship W2318380815A5005292574 @default.
- W2318380815 hasAuthorship W2318380815A5012677271 @default.
- W2318380815 hasAuthorship W2318380815A5058123246 @default.
- W2318380815 hasAuthorship W2318380815A5060002817 @default.
- W2318380815 hasAuthorship W2318380815A5065058975 @default.
- W2318380815 hasAuthorship W2318380815A5066591741 @default.
- W2318380815 hasAuthorship W2318380815A5076959779 @default.
- W2318380815 hasAuthorship W2318380815A5078526337 @default.
- W2318380815 hasConcept C154317977 @default.
- W2318380815 hasConcept C185592680 @default.
- W2318380815 hasConcept C202751555 @default.
- W2318380815 hasConcept C2776211264 @default.
- W2318380815 hasConcept C2779243328 @default.
- W2318380815 hasConcept C55493867 @default.
- W2318380815 hasConcept C556039675 @default.
- W2318380815 hasConcept C71240020 @default.
- W2318380815 hasConcept C71924100 @default.
- W2318380815 hasConceptScore W2318380815C154317977 @default.
- W2318380815 hasConceptScore W2318380815C185592680 @default.
- W2318380815 hasConceptScore W2318380815C202751555 @default.
- W2318380815 hasConceptScore W2318380815C2776211264 @default.
- W2318380815 hasConceptScore W2318380815C2779243328 @default.
- W2318380815 hasConceptScore W2318380815C55493867 @default.
- W2318380815 hasConceptScore W2318380815C556039675 @default.
- W2318380815 hasConceptScore W2318380815C71240020 @default.
- W2318380815 hasConceptScore W2318380815C71924100 @default.
- W2318380815 hasIssue "3" @default.
- W2318380815 hasLocation W23183808151 @default.
- W2318380815 hasOpenAccess W2318380815 @default.
- W2318380815 hasPrimaryLocation W23183808151 @default.
- W2318380815 hasRelatedWork W1966082953 @default.
- W2318380815 hasRelatedWork W1974980424 @default.
- W2318380815 hasRelatedWork W1982987349 @default.
- W2318380815 hasRelatedWork W2017018423 @default.
- W2318380815 hasRelatedWork W2049373169 @default.
- W2318380815 hasRelatedWork W2086405455 @default.
- W2318380815 hasRelatedWork W2148983524 @default.
- W2318380815 hasRelatedWork W2593859975 @default.
- W2318380815 hasRelatedWork W2950401271 @default.
- W2318380815 hasRelatedWork W2950548556 @default.
- W2318380815 hasVolume "10" @default.
- W2318380815 isParatext "false" @default.
- W2318380815 isRetracted "false" @default.
- W2318380815 magId "2318380815" @default.
- W2318380815 workType "article" @default.