Matches in SemOpenAlex for { <https://semopenalex.org/work/W2318392864> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2318392864 endingPage "295" @default.
- W2318392864 startingPage "291" @default.
- W2318392864 abstract "Moyamoya disease is a unique disease of unknown etiology typically characterized by progressive occlusion of both internal carotid arteries accompanied by an abnormal collateral circulation referred to as moyamoya vessels. To compensate for lack of blood flow in the frontal region, the collateral circulation develops from delicate basal networks and the vertebrobasilar system, and often is demonstrated by angiography, MRI or MRA. To investigate whether nitric oxide (NO) contributes to formation of abnormal collateral circulation in patients with moyamoya disease, we measured concentrations of NO metabolites in cerebrospinal fluid (CSF) obtained during treatment of this disease with bypass surgery.CSF samples were obtained from the subarachnoid space of the sylvian fissure during combined bypass surgery for moyamoya disease and kept frozen untill NO metabolites, nitrate and nitrite were measured using a Griess method.Compared with control specimens of CSF obtained from 16 patients with hemifacial spasm (n=8), trigeminal neuralgia (n=2), nonruptured aneurysm (n=5), or tremor (n=1), concentrations of NO metabolites in the CSF of 23 patients with moyamoya disease were significantly higher (18.6+1.1 vs. 11.0+1.0μM). NO metabolite concentrations (21.6+2.3μM) in CSF obtained during initial surgery in 7 resampled patients decreased to 16.9+1.5 μM in CSF obtained during a second, contralateral precedure. Angiographically early moyamoya disease tended to show lower concentrations of NO metabolites than cases of with greater development of moyamoya vessels.NO concentrations in CSF were chronically elevated in moyamoya disease, probably reflecting development of collateral circulation. Vascular bypass surgery can reduce NO metabolites together with abnormal collateral circulation." @default.
- W2318392864 created "2016-06-24" @default.
- W2318392864 creator A5002863379 @default.
- W2318392864 creator A5005970624 @default.
- W2318392864 creator A5022993769 @default.
- W2318392864 creator A5044701938 @default.
- W2318392864 creator A5079617036 @default.
- W2318392864 creator A5082035600 @default.
- W2318392864 date "1999-01-01" @default.
- W2318392864 modified "2023-09-25" @default.
- W2318392864 title "Do Nitric Oxide Metabolites in CSF Reflect the Development of Abnormal Collateral Circulation in Moyamoya Disease?" @default.
- W2318392864 doi "https://doi.org/10.2335/scs1987.27.4_291" @default.
- W2318392864 hasPublicationYear "1999" @default.
- W2318392864 type Work @default.
- W2318392864 sameAs 2318392864 @default.
- W2318392864 citedByCount "0" @default.
- W2318392864 crossrefType "journal-article" @default.
- W2318392864 hasAuthorship W2318392864A5002863379 @default.
- W2318392864 hasAuthorship W2318392864A5005970624 @default.
- W2318392864 hasAuthorship W2318392864A5022993769 @default.
- W2318392864 hasAuthorship W2318392864A5044701938 @default.
- W2318392864 hasAuthorship W2318392864A5079617036 @default.
- W2318392864 hasAuthorship W2318392864A5082035600 @default.
- W2318392864 hasBestOaLocation W23183928641 @default.
- W2318392864 hasConcept C126322002 @default.
- W2318392864 hasConcept C164705383 @default.
- W2318392864 hasConcept C2776548475 @default.
- W2318392864 hasConcept C2776599846 @default.
- W2318392864 hasConcept C2778749279 @default.
- W2318392864 hasConcept C2779651940 @default.
- W2318392864 hasConcept C2780643987 @default.
- W2318392864 hasConcept C71924100 @default.
- W2318392864 hasConceptScore W2318392864C126322002 @default.
- W2318392864 hasConceptScore W2318392864C164705383 @default.
- W2318392864 hasConceptScore W2318392864C2776548475 @default.
- W2318392864 hasConceptScore W2318392864C2776599846 @default.
- W2318392864 hasConceptScore W2318392864C2778749279 @default.
- W2318392864 hasConceptScore W2318392864C2779651940 @default.
- W2318392864 hasConceptScore W2318392864C2780643987 @default.
- W2318392864 hasConceptScore W2318392864C71924100 @default.
- W2318392864 hasIssue "4" @default.
- W2318392864 hasLocation W23183928641 @default.
- W2318392864 hasOpenAccess W2318392864 @default.
- W2318392864 hasPrimaryLocation W23183928641 @default.
- W2318392864 hasRelatedWork W1967505995 @default.
- W2318392864 hasRelatedWork W2017475411 @default.
- W2318392864 hasRelatedWork W2063548999 @default.
- W2318392864 hasRelatedWork W2068250619 @default.
- W2318392864 hasRelatedWork W2104536909 @default.
- W2318392864 hasRelatedWork W2130017235 @default.
- W2318392864 hasRelatedWork W2165532724 @default.
- W2318392864 hasRelatedWork W2359291404 @default.
- W2318392864 hasRelatedWork W2410580169 @default.
- W2318392864 hasRelatedWork W2411071859 @default.
- W2318392864 hasVolume "27" @default.
- W2318392864 isParatext "false" @default.
- W2318392864 isRetracted "false" @default.
- W2318392864 magId "2318392864" @default.
- W2318392864 workType "article" @default.