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- W2318405164 abstract "Introduction : The clinical picture of acute disseminated encephalomyelitis is characterized not only by a variety of neurological signs, but also by disorders of higher cortical functi ons. Disorders of higher cognitive functions often remain undetected during routine examination of patients and the use of specialized neuropsychological tests enables timely diagnosis of cognitive disorders. Methods: The assessment of cognitive impairment was carried out in 67 patients with ADEM (28 male and 39 female, aged 16 – 50, mean age - 31.6 ± 2.3). All the patients were being treated at the Kiev city centre of multiple sclerosis (Ukraine). The diagnosis of ADEM was based on neurological examination, MRI of the brain and CSF analysis. The cognitive impairment in patients with ADEM was assessed during the first three days after the onset of the disease. The neurological status was assessed by Kurtzke an Expanded Disability Status Scale (EDSS) and Functi onal Systems Scores (FSS). Patients performed neuropsychological tests that enabled evaluation of short - term and long term visual and auditory memory, various parameters of attention as well as ability to concentrate, orientation in time and space. Result s: The assessment of cognitive functions in patients with ADEM demonstrated impaired short - term and long - term memory indices according to “memorizing 10 words” test (34.6 ± 1.5 words compared with control 42.7±1 words, P <0.001), verbal learning and delayed recall according to California Verbal Learning Test (12.3±1.9 words compared to control 14 . 6±1 . 1 words, P <0,01) and sustained attention and concentration according to Symbol Digit Modalities Test (54.5±10.2" @default.
- W2318405164 created "2016-06-24" @default.
- W2318405164 creator A5031785549 @default.
- W2318405164 date "2015-01-10" @default.
- W2318405164 modified "2023-10-17" @default.
- W2318405164 title "The Characteristics of Cognitive Functions in Patients with Acute Disseminated Encephalomyelitis" @default.
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- W2318405164 doi "https://doi.org/10.9734/indj/2015/15286" @default.
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