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- W2318408054 abstract "Although cholesterol plays significant biochemical function in the human body, excess of it leads to various disorders, and thus, its control/separation is important in medical science and food industries. However, efficient and selective separation of cholesterol is challenging because cholesterol often exists in microheterogeneous or insoluble forms in remote organ and exists with other chemicals/biochemicals. Here, we have described a colloidal magnetic mesoporous silica (MMS)-based approach for efficient separation of cholesterol in different forms. MMS is functionalized with β-cyclodextrin for selective binding with cholesterol via host-guest interaction. The colloidal form of MMS offers effective interaction with cholesterol of any form, and magnetic property of MMS offers easier separation of bound cholesterol. Functionalized MMS is efficient in separating cholesterol crystals, water-insoluble cholesterol, and the microheterogeneous form of cholesterol from milk or a cellular environment. Developed material can be used to remove cholesterol from a complex bioenvironment and extended for large-scale cholesterol separation from food." @default.
- W2318408054 created "2016-06-24" @default.
- W2318408054 creator A5008830216 @default.
- W2318408054 creator A5054507147 @default.
- W2318408054 creator A5068599351 @default.
- W2318408054 creator A5090590717 @default.
- W2318408054 date "2015-01-08" @default.
- W2318408054 modified "2023-09-26" @default.
- W2318408054 title "β-Cyclodextrin Functionalized Magnetic Mesoporous Silica Colloid for Cholesterol Separation" @default.
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- W2318408054 doi "https://doi.org/10.1021/am507817b" @default.
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