FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2318440059> ?p ?o ?g. }

• W2318440059 endingPage "254" @default.
• W2318440059 startingPage "243" @default.
• W2318440059 abstract "T cells are involved in the homeostasis of periodontal tissues and mediate bone loss in periodontitis, but the involvement of T-helper cells in chronic periodontitis (CP) in a Chinese population is still unclear. This study aimed to assess the distribution of peripheral and local T helper (Th17) and Th1 in CP. Sixty-eight patients with CP and 43 healthy controls were recruited from April 2012 to July 2014 at the Department of Stomatology, People's Hospital of Xinjiang Uygur Autonomous Region (China). The proportions of Th17 (CD3(+)CD4(+)IL-17(+)) and Th1 (CD3(+)CD4(+)IFN-γ(+)) T-cells in peripheral blood samples were assessed by flow cytometry. Immunohistochemistry was used to quantify interleukin-17 (IL-17) and interferon-gamma (IFN-γ) protein levels in gingival biopsy samples. mRNA levels of IL-17, IFN-γ RORγt, and T-bet in gingival biopsy samples were measured by quantitative real-time polymerase chain reaction (qRT-PCR). The proportions of circulating Th17 cells and Th1 cells were both more abundant in CP patients than in controls (Th17: 1.05% ± 0.87% vs. 0.62% ± 0.49%, P < 0.01; Th1: 13.93% ± 7.94% vs. 8.22% ± 4.50%, P < 0.001). Positive correlations were obtained between the proportion of circulating Th17 cells and probing depth (PD) (r = 0.320, P = 0.001) and between the proportion of circulating Th1 cells and PD (r = 0.372, P < 0.001). IL-17 and IFN-γ protein levels in gingival biopsy samples were markedly increased in CP compared to controls (both P < 0.05). Relative IFN-γ, IL-17A, and T-bet mRNA levels in CP biopsies were higher compared to controls (all P < 0.05). These results suggest that elevated peripheral and local Th17 and Th1 cells might be involved in the pathogenesis of CP." @default.
• W2318440059 created "2016-06-24" @default.
• W2318440059 creator A5011713725 @default.
• W2318440059 creator A5020302124 @default.
• W2318440059 creator A5029893265 @default.
• W2318440059 creator A5031201491 @default.
• W2318440059 creator A5039096170 @default.
• W2318440059 creator A5071793998 @default.
• W2318440059 date "2016-03-28" @default.
• W2318440059 modified "2023-10-17" @default.
• W2318440059 title "Th17 and Th1 Lymphocytes Are Correlated with Chronic Periodontitis" @default.
• W2318440059 cites W1639854378 @default.
• W2318440059 cites W1963728950 @default.
• W2318440059 cites W1984631633 @default.
• W2318440059 cites W1987455407 @default.
• W2318440059 cites W1987628377 @default.
• W2318440059 cites W1991178845 @default.
• W2318440059 cites W1996855790 @default.
• W2318440059 cites W1999839870 @default.
• W2318440059 cites W2017783779 @default.
• W2318440059 cites W2021847466 @default.
• W2318440059 cites W2026379510 @default.
• W2318440059 cites W2036608242 @default.
• W2318440059 cites W2039395305 @default.
• W2318440059 cites W2049852383 @default.
• W2318440059 cites W2063329408 @default.
• W2318440059 cites W2074780505 @default.
• W2318440059 cites W2076889715 @default.
• W2318440059 cites W2082615180 @default.
• W2318440059 cites W2104650599 @default.
• W2318440059 cites W2118470591 @default.
• W2318440059 cites W2132019676 @default.
• W2318440059 cites W2142088734 @default.
• W2318440059 cites W2146805064 @default.
• W2318440059 cites W2147770922 @default.
• W2318440059 cites W2156451877 @default.
• W2318440059 cites W2158345683 @default.
• W2318440059 cites W2159326694 @default.
• W2318440059 cites W2162257591 @default.
• W2318440059 cites W2415027447 @default.
• W2318440059 doi "https://doi.org/10.3109/08820139.2016.1138967" @default.
• W2318440059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27019379" @default.
• W2318440059 hasPublicationYear "2016" @default.
• W2318440059 type Work @default.
• W2318440059 sameAs 2318440059 @default.
• W2318440059 citedByCount "44" @default.
• W2318440059 countsByYear W23184400592016 @default.
• W2318440059 countsByYear W23184400592017 @default.
• W2318440059 countsByYear W23184400592018 @default.
• W2318440059 countsByYear W23184400592019 @default.
• W2318440059 countsByYear W23184400592020 @default.
• W2318440059 countsByYear W23184400592021 @default.
• W2318440059 countsByYear W23184400592022 @default.
• W2318440059 countsByYear W23184400592023 @default.
• W2318440059 crossrefType "journal-article" @default.
• W2318440059 hasAuthorship W2318440059A5011713725 @default.
• W2318440059 hasAuthorship W2318440059A5020302124 @default.
• W2318440059 hasAuthorship W2318440059A5029893265 @default.
• W2318440059 hasAuthorship W2318440059A5031201491 @default.
• W2318440059 hasAuthorship W2318440059A5039096170 @default.
• W2318440059 hasAuthorship W2318440059A5071793998 @default.
• W2318440059 hasConcept C114684123 @default.
• W2318440059 hasConcept C126322002 @default.
• W2318440059 hasConcept C156730664 @default.
• W2318440059 hasConcept C167672396 @default.
• W2318440059 hasConcept C203014093 @default.
• W2318440059 hasConcept C2775934546 @default.
• W2318440059 hasConcept C2776914184 @default.
• W2318440059 hasConcept C2779337755 @default.
• W2318440059 hasConcept C2780385504 @default.
• W2318440059 hasConcept C2908647359 @default.
• W2318440059 hasConcept C47348012 @default.
• W2318440059 hasConcept C553184892 @default.
• W2318440059 hasConcept C71924100 @default.
• W2318440059 hasConcept C8891405 @default.
• W2318440059 hasConcept C99454951 @default.
• W2318440059 hasConceptScore W2318440059C114684123 @default.
• W2318440059 hasConceptScore W2318440059C126322002 @default.
• W2318440059 hasConceptScore W2318440059C156730664 @default.
• W2318440059 hasConceptScore W2318440059C167672396 @default.
• W2318440059 hasConceptScore W2318440059C203014093 @default.
• W2318440059 hasConceptScore W2318440059C2775934546 @default.
• W2318440059 hasConceptScore W2318440059C2776914184 @default.
• W2318440059 hasConceptScore W2318440059C2779337755 @default.
• W2318440059 hasConceptScore W2318440059C2780385504 @default.
• W2318440059 hasConceptScore W2318440059C2908647359 @default.
• W2318440059 hasConceptScore W2318440059C47348012 @default.
• W2318440059 hasConceptScore W2318440059C553184892 @default.
• W2318440059 hasConceptScore W2318440059C71924100 @default.
• W2318440059 hasConceptScore W2318440059C8891405 @default.
• W2318440059 hasConceptScore W2318440059C99454951 @default.
• W2318440059 hasFunder F4320321001 @default.
• W2318440059 hasFunder F4320336024 @default.
• W2318440059 hasFunder F4320338110 @default.
• W2318440059 hasIssue "3" @default.
• W2318440059 hasLocation W23184400591 @default.
• W2318440059 hasLocation W23184400592 @default.
• W2318440059 hasOpenAccess W2318440059 @default.

• next