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• W2318443670 abstract "“Smart” peptides that lyse membranes in response to biological stimuli are of considerable interest. Herein, we report a facile synthesis of l-tetrafluorotyrosine (l-f4Y) and its utilization as a pH sensing element. The synthetic route affords gram quantities of l-f4Y within two days. Incorporation of this unnatural amino acid into magainin 2 gives a peptide that turns on its membrane-lytic activity upon mild acidification." @default.
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• W2318443670 date "2010-12-10" @default.
• W2318443670 modified "2023-10-18" @default.
• W2318443670 title "Facile Synthesis of Tetrafluorotyrosine and Its Application in pH Triggered Membrane Lysis" @default.
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• W2318443670 doi "https://doi.org/10.1021/ol102610q" @default.
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