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• W2318447725 startingPage "1218" @default.
• W2318447725 abstract "Glass capillary based microfluidic devices are able to create extremely uniform droplets, when formed under the dripping regime, at low setup costs due to their ease of manufacture. However, as they are rarely parallelized, simple methods to increase droplet production from a single device are sought. Surfactants used to stabilize drops in such systems often limit the maximum flow rate that highly uniform drops can be produced due to the lowering interfacial tension causing jetting. In this paper we show that by simple design changes we can limit the interactions of surfactants and maximize uniform droplet production. Three flow-focused configurations are explored: a standard glass capillary device (consisting of a single round capillary inserted into a square capillary), a nozzle fed device, and a surfactant shielding device (both consisting of two round capillaries inserted into either end of a square capillary). In principle, the maximum productivity of uniform droplets is achieved if surfactants are not present. It was found that surfactants in the standard device greatly inhibit droplet production by means of interfacial tension lowering and tip-streaming phenomena. In the nozzle fed configuration, surfactant interactions were greatly limited, yielding flow rates comparable to, but lower than, a surfactant-free system. In the surfactant shielding configuration, flow rates were equal to that of a surfactant-free system and could make uniform droplets at rates an order of magnitude above the standard surfactant system." @default.
• W2318447725 created "2016-06-24" @default.
• W2318447725 creator A5020567214 @default.
• W2318447725 creator A5052609105 @default.
• W2318447725 date "2015-01-09" @default.
• W2318447725 modified "2023-09-26" @default.
• W2318447725 title "Increased Drop Formation Frequency via Reduction of Surfactant Interactions in Flow-Focusing Microfluidic Devices" @default.
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• W2318447725 doi "https://doi.org/10.1021/la504299r" @default.
• W2318447725 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25517938" @default.
• W2318447725 hasPublicationYear "2015" @default.
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