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- W2318501893 abstract "Orofacial odontogenic infections are usually treated with a β-lactam antibiotic. Most majorpathogens are susceptible to β-lactam antibiotics, although Prevotella species have been reported to produce β-lactamase and be resistant to β-lactam antibiotics. The purpose of this study was to evaluate β-lactamase production and antimicrobial susceptibility to 12 β-lactam antibiotics of Prevotella speciesisolated from 128 orofacial odontogenic infections. We confirmed that only Prevotella species were β-lactamasepositive in most isolates. Overall, 43.7% of pigmented Prevotella and 34.8% of nonpigmented Prevotella were positive for β-lactamase. The β-lactamase-positive strains were resistant to most of theantibiotics tested. However, piperacillin/tazobactam, cefmetazole, and faropenem showed antimicrobialactivity against these strains. In conclusion, this study shows the importance of β-lactamase-producing Prevotella strains in odontogenic infections and the need for appropriate choice of antibiotic." @default.
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- W2318501893 date "2002-01-01" @default.
- W2318501893 modified "2023-10-01" @default.
- W2318501893 title ".BETA.-lactamase production and antimicrobial susceptibility to .BETA.-lactam antibiotics of Prevotella isolated from orofacial odontogenic infections." @default.
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- W2318501893 doi "https://doi.org/10.5794/jjoms.48.379" @default.
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