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• W2318505514 abstract "BackgroundAtrial fibrillation is a known risk factor for thromboembolism. D-dimer levels reflect a pro-thrombogenic state and thus might serve as another marker of warfarin control.AimThis study investigated the correlation of warfarin control marker;PT-INR and pro-thromboembolic marker; D-dimer in patients with atrial fiblliration during oral anticoagulant therapy. Method:This was a single center, retrospective study. Patients with atrial fibrillation (57 males,17 females, mean age 71.8±8.7 years ) treated with warfarin (target PT-INR: 1.5 to 3.0) were included in this investigation based on the medical chart. D-dimer levels and PT-INR were measured, and followed up to June 2014.ResultThe correlation of PT-INR and D-dimer in all patients statistically was found. Espacially the negative relationship between PT-INR and D-dimer in subgroup patients, elderly patients (over 75 years); 28, hypertension patients; 57, patients were statistically found.ConclusionThe correlation of PT-INR and D-dimer in patients of atrial fibrillation was found and thus D-dimer also can serve as surrogate marker of warfarin control. BackgroundAtrial fibrillation is a known risk factor for thromboembolism. D-dimer levels reflect a pro-thrombogenic state and thus might serve as another marker of warfarin control. Atrial fibrillation is a known risk factor for thromboembolism. D-dimer levels reflect a pro-thrombogenic state and thus might serve as another marker of warfarin control. AimThis study investigated the correlation of warfarin control marker;PT-INR and pro-thromboembolic marker; D-dimer in patients with atrial fiblliration during oral anticoagulant therapy. Method:This was a single center, retrospective study. Patients with atrial fibrillation (57 males,17 females, mean age 71.8±8.7 years ) treated with warfarin (target PT-INR: 1.5 to 3.0) were included in this investigation based on the medical chart. D-dimer levels and PT-INR were measured, and followed up to June 2014. This study investigated the correlation of warfarin control marker;PT-INR and pro-thromboembolic marker; D-dimer in patients with atrial fiblliration during oral anticoagulant therapy. Method:This was a single center, retrospective study. Patients with atrial fibrillation (57 males,17 females, mean age 71.8±8.7 years ) treated with warfarin (target PT-INR: 1.5 to 3.0) were included in this investigation based on the medical chart. D-dimer levels and PT-INR were measured, and followed up to June 2014. ResultThe correlation of PT-INR and D-dimer in all patients statistically was found. Espacially the negative relationship between PT-INR and D-dimer in subgroup patients, elderly patients (over 75 years); 28, hypertension patients; 57, patients were statistically found. The correlation of PT-INR and D-dimer in all patients statistically was found. Espacially the negative relationship between PT-INR and D-dimer in subgroup patients, elderly patients (over 75 years); 28, hypertension patients; 57, patients were statistically found. ConclusionThe correlation of PT-INR and D-dimer in patients of atrial fibrillation was found and thus D-dimer also can serve as surrogate marker of warfarin control. The correlation of PT-INR and D-dimer in patients of atrial fibrillation was found and thus D-dimer also can serve as surrogate marker of warfarin control." @default.
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• W2318505514 date "2014-10-01" @default.
• W2318505514 modified "2023-09-27" @default.
• W2318505514 title "Surrogate Marker of Warfarin Control in Patients with Atrial Fiblliration" @default.
• W2318505514 doi "https://doi.org/10.1016/j.cardfail.2014.07.356" @default.
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