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- W2318618446 abstract "SummaryA method is described for detecting an aldosterone antagonist in unanesthetized adrenalectomized dogs maintained on long-acting replacement therapy. Using this method, spironolactone blocked mineralocorticoid effects on both Na and K excretion. The characteristics of the aldosterone antagonist were readily differentiated from those of a diuretic, chlorothiazide, by demonstration of qualitatively different effects on K excretion." @default.
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- W2318618446 date "1968-10-01" @default.
- W2318618446 modified "2023-09-25" @default.
- W2318618446 title "Determination of Antialdosterone Activity in Adrenalectomized Dogs" @default.
- W2318618446 doi "https://doi.org/10.3181/00379727-129-33240" @default.
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