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• W2318646537 abstract "Balancing pain relief against gastrointestinal side effects of opioid analgesics is a major challenge, a nationwide survey of nearly 6,000 physicians suggests. A total of 70% of physicians said they “usually” or “often” prescribe opioid analgesics for patients with moderate to severe acute pain. Alongside that, 63% said they also “usually” or “often” prescribe or recommend treatments to manage opioid-related side effects, especially gastrointestinal (GI) side effects, Dr. Bill H. McCarberg and his associates reported in a poster presentation at the annual meeting of the American Academy of Pain Medicine. Two-thirds of physicians said that patients who receive opioid analgesics also get over-the-counter or prescription treatments to manage GI side effects. A total of 60% of physicians rated unacceptable GI side effects as the top reason or the second-to-the-top reason for discontinuing opioids, reported Dr. McCarberg, a family physician and pain specialist at Kaiser Permanente, San Diego. The data came from the Physicians Partnering Against Pain survey of 5,982 physicians. A majority of respondents (52%) were primary care physicians, and 25% were pain specialists. More than 40% of physicians said that patients discontinued opioids mainly because they believed that their pain had dissipated. More than 15% of physicians said that they see more than 60 patients with moderate to severe pain in a typical week. More than 20% said they see 31–60 patients per week, more than 35% said they see 16–30 patients per week, and nearly 25% said they see 0–15 patients with moderate to severe pain in a typical week. The participating physicians may not be representative of all U.S. practicing physicians, and there may be some recall bias affecting how well the results represent actual physician behavior. However, the findings reflect the significant challenges that opioid-related side effects pose for managing moderate to severe acute pain, Dr. McCarberg said. Janssen Scientific Affairs funded the study, and Dr. McCarberg's associates in the study were Janssen employees. Dr. McCarberg reported having no financial conflict of interest." @default.
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• W2318646537 date "2012-06-01" @default.
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• W2318646537 title "Side Effects Challenge Opioid Therapy for Acute Pain" @default.
• W2318646537 doi "https://doi.org/10.1016/j.carage.2012.06.011" @default.
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