FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2318671960> ?p ?o ?g. }

• W2318671960 endingPage "395" @default.
• W2318671960 startingPage "385" @default.
• W2318671960 abstract "The nematode C. elegans develops through four larval stages before it reaches adulthood. At the transition between stages and before it sheds its cuticle, it exhibits a sleep-like behavior during a stage termed lethargus. The objectives of this study were to characterize in detail behavioral patterns and physiological activity of a command interneuron during lethargus.We found that lethargus behavior was composed of bouts of quiescence and motion. The duration of individual bouts ranged from 2 to 100 seconds, and their dynamics exhibited local homeostasis: the duration of bouts of quiescence positively correlated with the duration of bouts of motion that immediately preceded them in a cAMP-dependent manner. In addition, we identified a characteristic body posture during lethargus: the average curvature along the body of L4 lethargus larvae was lower than that of L4 larvae prior to lethargus, and the positions of body bends were distributed non-uniformly along the bodies of quiescent animals. Finally, we found that the AVA interneurons, a pair of backward command neurons, mediated locomotion patterns during L4 lethargus in similar fashion to their function in L4 larvae prior to lethargus. Interestingly, in both developmental stages backward locomotion was initiated and terminated asymmetrically with respect to AVA intraneuronal calcium concentration.The complex behavioral patterns during lethargus can be dissected to quantifiable elements, which exhibit rich temporal dynamics and are actively regulated by the nervous system. Our findings support the identification of lethargus as a sleep-like state.Iwanir S; Tramm N; Nagy S; Wright C; Ish D; Biron D. The microarchitecture of C. elegans behavior during lethargus: homeostatic bout dynamics, a typical body posture, and regulation by a central neuron. SLEEP 2013;36(3):385-395." @default.
• W2318671960 created "2016-06-24" @default.
• W2318671960 creator A5012978703 @default.
• W2318671960 creator A5017751394 @default.
• W2318671960 creator A5022330816 @default.
• W2318671960 creator A5057241510 @default.
• W2318671960 creator A5058892611 @default.
• W2318671960 creator A5086745994 @default.
• W2318671960 date "2013-03-01" @default.
• W2318671960 modified "2023-10-12" @default.
• W2318671960 title "The Microarchitecture of C. elegans Behavior during Lethargus: Homeostatic Bout Dynamics, a Typical Body Posture, and Regulation by a Central Neuron" @default.
• W2318671960 cites W1503250866 @default.
• W2318671960 cites W1586783369 @default.
• W2318671960 cites W178779372 @default.
• W2318671960 cites W1889720390 @default.
• W2318671960 cites W1904905451 @default.
• W2318671960 cites W1944127002 @default.
• W2318671960 cites W1968335909 @default.
• W2318671960 cites W1980155359 @default.
• W2318671960 cites W1980317846 @default.
• W2318671960 cites W1983062910 @default.
• W2318671960 cites W1985294550 @default.
• W2318671960 cites W1986033302 @default.
• W2318671960 cites W1994557483 @default.
• W2318671960 cites W1996237495 @default.
• W2318671960 cites W1999030021 @default.
• W2318671960 cites W2003469902 @default.
• W2318671960 cites W2013541600 @default.
• W2318671960 cites W2016016611 @default.
• W2318671960 cites W2022087979 @default.
• W2318671960 cites W2028184697 @default.
• W2318671960 cites W2031012150 @default.
• W2318671960 cites W2041017511 @default.
• W2318671960 cites W2054014550 @default.
• W2318671960 cites W2058615553 @default.
• W2318671960 cites W2061406005 @default.
• W2318671960 cites W2070217895 @default.
• W2318671960 cites W2072474554 @default.
• W2318671960 cites W2072681733 @default.
• W2318671960 cites W2074343841 @default.
• W2318671960 cites W2074371112 @default.
• W2318671960 cites W2076397118 @default.
• W2318671960 cites W2076792376 @default.
• W2318671960 cites W2083726130 @default.
• W2318671960 cites W2094409491 @default.
• W2318671960 cites W2095985961 @default.
• W2318671960 cites W2096109037 @default.
• W2318671960 cites W2098923623 @default.
• W2318671960 cites W2100272988 @default.
• W2318671960 cites W2108010346 @default.
• W2318671960 cites W2109234881 @default.
• W2318671960 cites W2116086925 @default.
• W2318671960 cites W2119515379 @default.
• W2318671960 cites W2119706891 @default.
• W2318671960 cites W2124676062 @default.
• W2318671960 cites W2126902054 @default.
• W2318671960 cites W2129420942 @default.
• W2318671960 cites W2131096662 @default.
• W2318671960 cites W2139004484 @default.
• W2318671960 cites W2140961130 @default.
• W2318671960 cites W2142254043 @default.
• W2318671960 cites W2142331710 @default.
• W2318671960 cites W2147515706 @default.
• W2318671960 cites W2154389993 @default.
• W2318671960 cites W2157127963 @default.
• W2318671960 cites W2160938187 @default.
• W2318671960 cites W2162319224 @default.
• W2318671960 cites W2169940731 @default.
• W2318671960 doi "https://doi.org/10.5665/sleep.2456" @default.
• W2318671960 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3571756" @default.
• W2318671960 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23449971" @default.
• W2318671960 hasPublicationYear "2013" @default.
• W2318671960 type Work @default.
• W2318671960 sameAs 2318671960 @default.
• W2318671960 citedByCount "80" @default.
• W2318671960 countsByYear W23186719602013 @default.
• W2318671960 countsByYear W23186719602014 @default.
• W2318671960 countsByYear W23186719602015 @default.
• W2318671960 countsByYear W23186719602016 @default.
• W2318671960 countsByYear W23186719602017 @default.
• W2318671960 countsByYear W23186719602018 @default.
• W2318671960 countsByYear W23186719602019 @default.
• W2318671960 countsByYear W23186719602020 @default.
• W2318671960 countsByYear W23186719602021 @default.
• W2318671960 countsByYear W23186719602022 @default.
• W2318671960 countsByYear W23186719602023 @default.
• W2318671960 crossrefType "journal-article" @default.
• W2318671960 hasAuthorship W2318671960A5012978703 @default.
• W2318671960 hasAuthorship W2318671960A5017751394 @default.
• W2318671960 hasAuthorship W2318671960A5022330816 @default.
• W2318671960 hasAuthorship W2318671960A5057241510 @default.
• W2318671960 hasAuthorship W2318671960A5058892611 @default.
• W2318671960 hasAuthorship W2318671960A5086745994 @default.
• W2318671960 hasBestOaLocation W23186719601 @default.
• W2318671960 hasConcept C104317684 @default.
• W2318671960 hasConcept C105702510 @default.
• W2318671960 hasConcept C134018914 @default.
• W2318671960 hasConcept C169760540 @default.

• next