Matches in SemOpenAlex for { <https://semopenalex.org/work/W2318673848> ?p ?o ?g. }
- W2318673848 endingPage "7755" @default.
- W2318673848 startingPage "7750" @default.
- W2318673848 abstract "In this work, we describe a new universal and highly sensitive strategy for electrochemiluminescent (ECL) detection of sequence specific DNA at the femtomolar level via in situ hybridization chain reaction (HCR) signal amplification. The DNA capture probes are self-assembled on a gold electrode. The presence of the target DNA and two hairpin helper DNAs leads to the formation of extended dsDNA polymers through HCR on the electrode surface. The in situ, HCR-generated dsDNA polymers cause the intercalation of numerous ECL indicators (Ru(phen)32+) into the dsDNA grooves, resulting in significantly amplified ECL signal output. The proposed strategy combines the amplification power of the DNA HCR and the inherent high sensitivity of the ECL technique and enables low femtomolar detection of sequence specific DNA. The developed strategy also shows high selectivity against single-base mismatch sequences, which makes our new universal and highly sensitive HCR-based method a useful addition to the amplified DNA detection arena." @default.
- W2318673848 created "2016-06-24" @default.
- W2318673848 creator A5007650182 @default.
- W2318673848 creator A5040558103 @default.
- W2318673848 creator A5057795872 @default.
- W2318673848 creator A5059434416 @default.
- W2318673848 creator A5065406334 @default.
- W2318673848 creator A5075456604 @default.
- W2318673848 date "2012-09-05" @default.
- W2318673848 modified "2023-10-18" @default.
- W2318673848 title "In Situ Hybridization Chain Reaction Amplification for Universal and Highly Sensitive Electrochemiluminescent Detection of DNA" @default.
- W2318673848 cites W1965541534 @default.
- W2318673848 cites W1971279231 @default.
- W2318673848 cites W1973459440 @default.
- W2318673848 cites W1979873498 @default.
- W2318673848 cites W1983437607 @default.
- W2318673848 cites W1984772187 @default.
- W2318673848 cites W1986644879 @default.
- W2318673848 cites W1986948090 @default.
- W2318673848 cites W1987702110 @default.
- W2318673848 cites W1994014422 @default.
- W2318673848 cites W1999575246 @default.
- W2318673848 cites W2002013713 @default.
- W2318673848 cites W2002096893 @default.
- W2318673848 cites W2005937212 @default.
- W2318673848 cites W2008262280 @default.
- W2318673848 cites W2008973858 @default.
- W2318673848 cites W2009040055 @default.
- W2318673848 cites W2009615238 @default.
- W2318673848 cites W2011151577 @default.
- W2318673848 cites W2012179886 @default.
- W2318673848 cites W2030911521 @default.
- W2318673848 cites W2032118018 @default.
- W2318673848 cites W2037269788 @default.
- W2318673848 cites W2039760586 @default.
- W2318673848 cites W2040570597 @default.
- W2318673848 cites W2042152855 @default.
- W2318673848 cites W2043487612 @default.
- W2318673848 cites W2043826407 @default.
- W2318673848 cites W2055839492 @default.
- W2318673848 cites W2061825664 @default.
- W2318673848 cites W2072378436 @default.
- W2318673848 cites W2074589577 @default.
- W2318673848 cites W2079400239 @default.
- W2318673848 cites W2079707634 @default.
- W2318673848 cites W2081844639 @default.
- W2318673848 cites W2087661789 @default.
- W2318673848 cites W2088195469 @default.
- W2318673848 cites W2094163052 @default.
- W2318673848 cites W2096328744 @default.
- W2318673848 cites W2108013644 @default.
- W2318673848 cites W2114566097 @default.
- W2318673848 cites W2122374036 @default.
- W2318673848 cites W2140964046 @default.
- W2318673848 cites W2142491192 @default.
- W2318673848 cites W2148304424 @default.
- W2318673848 cites W2148797807 @default.
- W2318673848 cites W2150648559 @default.
- W2318673848 cites W2151878885 @default.
- W2318673848 cites W2153321597 @default.
- W2318673848 cites W2320608037 @default.
- W2318673848 cites W2335715989 @default.
- W2318673848 doi "https://doi.org/10.1021/ac3012285" @default.
- W2318673848 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22924989" @default.
- W2318673848 hasPublicationYear "2012" @default.
- W2318673848 type Work @default.
- W2318673848 sameAs 2318673848 @default.
- W2318673848 citedByCount "262" @default.
- W2318673848 countsByYear W23186738482012 @default.
- W2318673848 countsByYear W23186738482013 @default.
- W2318673848 countsByYear W23186738482014 @default.
- W2318673848 countsByYear W23186738482015 @default.
- W2318673848 countsByYear W23186738482016 @default.
- W2318673848 countsByYear W23186738482017 @default.
- W2318673848 countsByYear W23186738482018 @default.
- W2318673848 countsByYear W23186738482019 @default.
- W2318673848 countsByYear W23186738482020 @default.
- W2318673848 countsByYear W23186738482021 @default.
- W2318673848 countsByYear W23186738482022 @default.
- W2318673848 countsByYear W23186738482023 @default.
- W2318673848 crossrefType "journal-article" @default.
- W2318673848 hasAuthorship W2318673848A5007650182 @default.
- W2318673848 hasAuthorship W2318673848A5040558103 @default.
- W2318673848 hasAuthorship W2318673848A5057795872 @default.
- W2318673848 hasAuthorship W2318673848A5059434416 @default.
- W2318673848 hasAuthorship W2318673848A5065406334 @default.
- W2318673848 hasAuthorship W2318673848A5075456604 @default.
- W2318673848 hasConcept C129312508 @default.
- W2318673848 hasConcept C130197536 @default.
- W2318673848 hasConcept C137390916 @default.
- W2318673848 hasConcept C137824038 @default.
- W2318673848 hasConcept C168931907 @default.
- W2318673848 hasConcept C171250308 @default.
- W2318673848 hasConcept C178790620 @default.
- W2318673848 hasConcept C179104552 @default.
- W2318673848 hasConcept C185592680 @default.
- W2318673848 hasConcept C192562407 @default.
- W2318673848 hasConcept C21951064 @default.