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• W2318781638 abstract "The development of the molecular biology techniques has made possible the study of the genetic background of American populations where a substantial contribution of the aboriginal component exists, but its individuals had lost the ethnic identity because of dramatic historical, cultural and social changes. The aim of the present work was to investigate the origin of the paternal lineages present in La Esperanza (Jujuy, Argentina), a population originated at the end of XVIII century as a consequence of the installation of a sugar plantation. DNA of 37 non-related males was purified from buccal swabs and subjected to STR PCR amplification of 11 Y chromosome loci using a commercial kit. In addition, 4 binary markers commonly used in diagnosis of ethnic origin (DYS199, M89, M207, and M173) were characterized by RFLP-PCR. From the 37 individuals analyzed, 34 different STRs based haplotypes were observed, 31 of them being unique, which shows the high heterogeneity of the genetic composition of the population. A search in the Y-Haplotype Chromosome Reference Database allowed to identify 11 Amerindian, 14 European, 2 Arabs and 2 Africans haplotypes. The 8 remaining haplotypes were not possible to assign unequivocally. On the other hand, the analysis of binary markers permits to include all the individuals analyzed (29) into a known haplogroup: 17 individuals carry the haplogroup Q1a3a (Amerindian), 9 the R1 (European), 1 the R (European) and 2 F (Eurasian). We conclude that the STRs and binary markers should be used jointly to get more accurate information about the ethnic origin and genetic diversity of human populations." @default.
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• W2318781638 date "2015-01-01" @default.
• W2318781638 modified "2023-10-14" @default.
• W2318781638 title "Forensic Science International: Genetics Supplement Series" @default.
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