Matches in SemOpenAlex for { <https://semopenalex.org/work/W2318842938> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2318842938 endingPage "966" @default.
- W2318842938 startingPage "965" @default.
- W2318842938 abstract "In Brief Study Design. Spine Update on prognostic scoring systems for spinal metastases in the era of anti-vascular endothelial growth factor (VEGF) therapies. Objective. To review and discuss the strengths and weaknesses of available scoring systems since the introduction of molecular targeted anticancer agents. Summary of Background Data. Molecular targeted anticancer agents have dramatically improved survival of patients in various cancers, including renal cancer. Methods. Using prognostic scoring systems for spinal metastases and recent survival data of patients with cancers treated with anti-VEGF agents, a review was undertaken, evaluating the strengths and weaknesses of available prognostic scoring systems designed in the 1990s and early 2000s among patients treated with recent agents (available from 2005). Results. All available prognostic scoring systems for spinal metastases include the primary tumor as a key variable. The estimation of life expectancy with these systems is inaccurate in view of recent survival data, as illustrated in renal cancer. The underestimation of life expectancy and subsequent inadequate treatment of spinal metastases may lead to dramatic alteration of the quality of life. Conclusion. The assessment of the available scores in recent cohorts of patients is mandatory to test their current validity and evidence the need for aggressive surgical management. New scoring systems taking into account the gain in survival induced by recent anticancer agents will likely be warranted in a close future. Anti-VEGF agents have dramatically improved the prognosis of various cancers, making obsolete the available prognostic scoring systems for spinal metastases. Patients with spinal metastases from tumors particularly sensitive to molecular targeted agents are at risk of being inadequately treated on the basis of poor estimation of life expectancy." @default.
- W2318842938 created "2016-06-24" @default.
- W2318842938 creator A5013591523 @default.
- W2318842938 creator A5014622100 @default.
- W2318842938 creator A5090375155 @default.
- W2318842938 date "2013-05-01" @default.
- W2318842938 modified "2023-10-17" @default.
- W2318842938 title "Prognostic Scoring Systems for Spinal Metastases in the Era of Anti-VEGF Therapies" @default.
- W2318842938 cites W1968341044 @default.
- W2318842938 cites W1999874349 @default.
- W2318842938 cites W2002004149 @default.
- W2318842938 cites W2003611671 @default.
- W2318842938 cites W2004128192 @default.
- W2318842938 cites W2009670669 @default.
- W2318842938 cites W2092307950 @default.
- W2318842938 cites W2121850852 @default.
- W2318842938 cites W2155688313 @default.
- W2318842938 doi "https://doi.org/10.1097/brs.0b013e3182609d38" @default.
- W2318842938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22648032" @default.
- W2318842938 hasPublicationYear "2013" @default.
- W2318842938 type Work @default.
- W2318842938 sameAs 2318842938 @default.
- W2318842938 citedByCount "28" @default.
- W2318842938 countsByYear W23188429382014 @default.
- W2318842938 countsByYear W23188429382015 @default.
- W2318842938 countsByYear W23188429382016 @default.
- W2318842938 countsByYear W23188429382017 @default.
- W2318842938 countsByYear W23188429382018 @default.
- W2318842938 countsByYear W23188429382019 @default.
- W2318842938 countsByYear W23188429382021 @default.
- W2318842938 countsByYear W23188429382022 @default.
- W2318842938 countsByYear W23188429382023 @default.
- W2318842938 crossrefType "journal-article" @default.
- W2318842938 hasAuthorship W2318842938A5013591523 @default.
- W2318842938 hasAuthorship W2318842938A5014622100 @default.
- W2318842938 hasAuthorship W2318842938A5090375155 @default.
- W2318842938 hasConcept C121608353 @default.
- W2318842938 hasConcept C126322002 @default.
- W2318842938 hasConcept C133925201 @default.
- W2318842938 hasConcept C143998085 @default.
- W2318842938 hasConcept C167734588 @default.
- W2318842938 hasConcept C177713679 @default.
- W2318842938 hasConcept C2908647359 @default.
- W2318842938 hasConcept C2984538763 @default.
- W2318842938 hasConcept C71924100 @default.
- W2318842938 hasConcept C99454951 @default.
- W2318842938 hasConceptScore W2318842938C121608353 @default.
- W2318842938 hasConceptScore W2318842938C126322002 @default.
- W2318842938 hasConceptScore W2318842938C133925201 @default.
- W2318842938 hasConceptScore W2318842938C143998085 @default.
- W2318842938 hasConceptScore W2318842938C167734588 @default.
- W2318842938 hasConceptScore W2318842938C177713679 @default.
- W2318842938 hasConceptScore W2318842938C2908647359 @default.
- W2318842938 hasConceptScore W2318842938C2984538763 @default.
- W2318842938 hasConceptScore W2318842938C71924100 @default.
- W2318842938 hasConceptScore W2318842938C99454951 @default.
- W2318842938 hasIssue "11" @default.
- W2318842938 hasLocation W23188429381 @default.
- W2318842938 hasLocation W23188429382 @default.
- W2318842938 hasOpenAccess W2318842938 @default.
- W2318842938 hasPrimaryLocation W23188429381 @default.
- W2318842938 hasRelatedWork W155501516 @default.
- W2318842938 hasRelatedWork W1964302512 @default.
- W2318842938 hasRelatedWork W2088728275 @default.
- W2318842938 hasRelatedWork W2276555056 @default.
- W2318842938 hasRelatedWork W257066 @default.
- W2318842938 hasRelatedWork W2903262747 @default.
- W2318842938 hasRelatedWork W2948525704 @default.
- W2318842938 hasRelatedWork W4206652754 @default.
- W2318842938 hasRelatedWork W4240111759 @default.
- W2318842938 hasRelatedWork W57840517 @default.
- W2318842938 hasVolume "38" @default.
- W2318842938 isParatext "false" @default.
- W2318842938 isRetracted "false" @default.
- W2318842938 magId "2318842938" @default.
- W2318842938 workType "article" @default.