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• W2318987911 abstract "Among mother–infant pairs, 5.0% of infants were HIV-1–positive at 2 weeks of life. The estimated risk of HIV-1 transmission between 2 and 28 weeks was higher in the control group (5.7%) than in either the maternal-regimen group (2.9%, P = 0.009) or the infant-regimen group (1.7%, P<0.001). The estimated risk of infant HIV-1 infection or death between 2 and 28 weeks was 7.0% in the control group, 4.1% in the maternal-regimen group (P = 0.02), and 2.6% in the infant-regimen group (P<0.001). The proportion of women with neutropenia was higher among those receiving the antiretroviral regimen (6.2%) than among those in either the nevirapine group (2.6%) or the control group (2.3%). Among infants receiving nevirapine, 1.9% had a hypersensitivity reaction. Conclusions The use of either a maternal antiretroviral regimen or infant nevirapine for 28 weeks was effective in reducing HIV-1 transmission during breast-feeding. (ClinicalTrials .gov number, NCT00164736.)" @default.
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• W2318987911 date "2010-11-01" @default.
• W2318987911 modified "2023-09-27" @default.
• W2318987911 title "Maternal or Infant Antiretroviral Drugs to Reduce HIV-1 Transmission" @default.
• W2318987911 doi "https://doi.org/10.1097/ogx.0b013e3182022051" @default.
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