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• W2318992507 abstract "Cattle husbandry is a major contributor to atmospheric methane, which is considered as an important greenhouse gas. Moreover, the generation of methane in the intestine of domestic ruminants by methanogenic bacteria is a drag on feed efficacy. Studies on methanogenesis have typically implied model organisms that are, however, not relevant in the ruminant gut. This paper shows that methyl-CoM reductase catalyzing the final step of methanogenesis in Methanobrevibacter ruminantium, a major participant in methane production by cattle, is inhibited by 2-bromoethanesulfonate, a compound often used as a model in animal agriculture, with an apparent IC50 of 0.4 ± 0.04 μM." @default.
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• W2318992507 date "2014-12-17" @default.
• W2318992507 modified "2023-10-13" @default.
• W2318992507 title "Inhibition of Methyl-CoM Reductase from <i>Methanobrevibacter ruminantium</i> by 2-Bromoethanesulfonate" @default.
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• W2318992507 doi "https://doi.org/10.1021/jf505056g" @default.
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