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- W2319120043 abstract "Scanning electron microscope observation was carried out to examine what happens in the glass bead columns during the platelet adhesiveness test. The columns were perfused with different volumes of blood from four normal subjects, and after perfusion of glutaraldehyde and acetone and air drying, the beads were partially embedded in epoxy resin. Bunches of the beads were cut out and their surfaces freed of resin contamination were observed.Many platelets and erythrocytes were found on the beads. The platelets showed different stages of a process in which, as in our previous experiment on the platelet attitude to glass plate, a few of them first adhered to the glass surface and then further platelets became attached to them, forming larger and larger aggregates. The aggregated platelets showed the same features as those in the ADP-induced primary aggregates in vitro. The erythrocytes were found to be attached to the glass, deformed into a drop-like shape and finally ruptured by blood flow.It was concluded that the result of this method mainly reflects the aggregation probably caused by ADP from hemolysis occurring on the beads." @default.
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- W2319120043 date "1974-01-01" @default.
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- W2319120043 title "Platelet Adhesion and Aggregation in the Glass Bead Column Method (HELLEM-II): A Scanning Electron Microscope Study" @default.
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- W2319120043 doi "https://doi.org/10.1679/aohc1950.36.323" @default.
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