Matches in SemOpenAlex for { <https://semopenalex.org/work/W2319323124> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2319323124 endingPage "504" @default.
- W2319323124 startingPage "495" @default.
- W2319323124 abstract "Liposomes of various physical and chemical compositions were prepared and their ability to externally bind and internally capture human interferon alpha (HuIFN-alpha) was determined. HuIFN-alpha was bound by preformed liposomes composed of either dipalmitoyl phosphatidyl choline alone or dipalmitoyl phosphatidic acid (calcium salt), and cholesterol, with or without a phosphatidyl choline component. HuIFN-alpha could also be internally captured within liposomes both of compositions that bound or did not bind interferon. The interferon could be associated with liposomes in at least three manners: bound to the outside surface of the liposome, associated partially within the liposomal membranes, or completely internalized either within the aqueous compartments of the liposome or completely buried within the liposomal bilayer membrane. HuIFN-alpha was stably-associated with reverse-evaporation vesicles, multilamellar vesicles, and small unilamellar vesicles for 30 days at 4 degrees C. Incubation of the multilamellar vesicles at 37 degrees C caused an initial decrease in the amount of externally bound interferon, and incubation with mouse serum caused a further dissociation of the externally-bound interferon. Depending on liposome composition, incubation at 37 degrees C either had little effect on stability of internalized interferon or caused leakage of internalized interferon." @default.
- W2319323124 created "2016-06-24" @default.
- W2319323124 creator A5003971010 @default.
- W2319323124 creator A5019817828 @default.
- W2319323124 date "1981-01-01" @default.
- W2319323124 modified "2023-09-24" @default.
- W2319323124 title "Binding and Capture of Human Interferon-Alpha by Reverse Evaporation Vesicles, Multilamellar Vesicles, and Small Unilamellar Vesicles" @default.
- W2319323124 cites W1973011792 @default.
- W2319323124 cites W1984277020 @default.
- W2319323124 cites W2001639887 @default.
- W2319323124 cites W2004355909 @default.
- W2319323124 cites W2022639798 @default.
- W2319323124 cites W2044569715 @default.
- W2319323124 cites W2066247783 @default.
- W2319323124 cites W2090371453 @default.
- W2319323124 cites W2104432380 @default.
- W2319323124 cites W2116628043 @default.
- W2319323124 cites W2178760081 @default.
- W2319323124 cites W2211773651 @default.
- W2319323124 doi "https://doi.org/10.1089/jir.1981.1.495" @default.
- W2319323124 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6180083" @default.
- W2319323124 hasPublicationYear "1981" @default.
- W2319323124 type Work @default.
- W2319323124 sameAs 2319323124 @default.
- W2319323124 citedByCount "26" @default.
- W2319323124 countsByYear W23193231242012 @default.
- W2319323124 countsByYear W23193231242017 @default.
- W2319323124 crossrefType "journal-article" @default.
- W2319323124 hasAuthorship W2319323124A5003971010 @default.
- W2319323124 hasAuthorship W2319323124A5019817828 @default.
- W2319323124 hasConcept C12554922 @default.
- W2319323124 hasConcept C130316041 @default.
- W2319323124 hasConcept C185154212 @default.
- W2319323124 hasConcept C185592680 @default.
- W2319323124 hasConcept C192157962 @default.
- W2319323124 hasConcept C203014093 @default.
- W2319323124 hasConcept C2776178377 @default.
- W2319323124 hasConcept C2776909261 @default.
- W2319323124 hasConcept C2778918659 @default.
- W2319323124 hasConcept C2909179924 @default.
- W2319323124 hasConcept C41625074 @default.
- W2319323124 hasConcept C55493867 @default.
- W2319323124 hasConcept C86803240 @default.
- W2319323124 hasConceptScore W2319323124C12554922 @default.
- W2319323124 hasConceptScore W2319323124C130316041 @default.
- W2319323124 hasConceptScore W2319323124C185154212 @default.
- W2319323124 hasConceptScore W2319323124C185592680 @default.
- W2319323124 hasConceptScore W2319323124C192157962 @default.
- W2319323124 hasConceptScore W2319323124C203014093 @default.
- W2319323124 hasConceptScore W2319323124C2776178377 @default.
- W2319323124 hasConceptScore W2319323124C2776909261 @default.
- W2319323124 hasConceptScore W2319323124C2778918659 @default.
- W2319323124 hasConceptScore W2319323124C2909179924 @default.
- W2319323124 hasConceptScore W2319323124C41625074 @default.
- W2319323124 hasConceptScore W2319323124C55493867 @default.
- W2319323124 hasConceptScore W2319323124C86803240 @default.
- W2319323124 hasIssue "4" @default.
- W2319323124 hasLocation W23193231241 @default.
- W2319323124 hasLocation W23193231242 @default.
- W2319323124 hasOpenAccess W2319323124 @default.
- W2319323124 hasPrimaryLocation W23193231241 @default.
- W2319323124 hasRelatedWork W1935563837 @default.
- W2319323124 hasRelatedWork W1998073612 @default.
- W2319323124 hasRelatedWork W2085917323 @default.
- W2319323124 hasRelatedWork W2086172883 @default.
- W2319323124 hasRelatedWork W2089532729 @default.
- W2319323124 hasRelatedWork W2095532026 @default.
- W2319323124 hasRelatedWork W2107870263 @default.
- W2319323124 hasRelatedWork W2133772902 @default.
- W2319323124 hasRelatedWork W2319323124 @default.
- W2319323124 hasRelatedWork W2321082801 @default.
- W2319323124 hasVolume "1" @default.
- W2319323124 isParatext "false" @default.
- W2319323124 isRetracted "false" @default.
- W2319323124 magId "2319323124" @default.
- W2319323124 workType "article" @default.