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• W2319325618 abstract "Event Abstract Back to Event Screw pull out under cyclic fatigue loading in synthetic, cadaveric, and canine bone Molly E. Baumann1 and Alan S. Litsky1, 2* 1 Ohio State University, Biomedical Engineering, United States 2 Ohio State University, Orthopaedics, United States Introduction: Fracture fixation devices are often used to reduce recovery time and regain function. Many tests on new devices are done on composite bones which are available and mechanically consistent. Zdero, et al., studied the screw pull-out, shear stress, and energy to failure in composite (Sawbones®) and cadaveric bones finding no statistical difference for these properties[1]. There has been no study comparing cadaveric and composite bone under cyclic loading and no study comparing composite and canine bones. Methods: Anterior-posterior holes were drilled 3 cm apart and tapped for 3.5 mm cortical bone screws which were inserted bicortically. Each test construct was loaded into a servohydraulic materials test frame [Bionix 858, MTS Corp, Eden Prairie, MN] with a custom-designed screw grip for axial alignment. Pull-out force was collected under displacement control at 0.1 mm/sec. For the fatigue loading tests, a 20 N pre-load was applied followed by a tensile cyclic load of 200-1000 N for 200,000 cycles at 7 Hz for the composite and cadaveric bone and at 2 Hz for the canine bone. Two sample t-tests were performed comparing the composite to the human and to the canine bone with a significance value of p = 0.05. Results: The screw pull-out force for the composite, human, and canine were 3894 N, 4746 N, and 1628 N respectively [Table 1]. The screw displacement with fatigue loading for the composite, human, and canine was 0.057 mm, 0.094 mm, and 1.039 mm respectively [Table 2]. The canine testing failed at 84,715 ± 68,312 cycles; the composite and human bones ran to completion. p-value < 0.05 in all comparisons. Discussion: There is a statistical difference between composite bones and cadaveric bones in regards to screw fatigue. The difference is not thought to be of clinical significance as the average pull-out of about 0.1 mm is not enough to cause failure over the time frame of a device. The canine bones showed significantly greater displacement before pull-out and failed under cyclic load; the composite specimens did neither. Conclusion: These composite bone models are widely used to test devices and the models had not been validated in terms of screw fatigue. This study suggests that they may not be accurate representations of fatigue behavior, particularly for canine studies. Table 1: Screw Pull-Out Force Newtons p-value Composite n = 8 3895 ± 451 Human n = 4 4746 ± 553 0.044 Canine n = 8 1629 ± 284 4.70E-08 Table 2: Fatigue Results Displacement p-value Cycles p-value Composite n=19 0.057 ± 0.0260 200,000 Human n=17 0.094 ± 0.0296 0.0004 200,000 Canine n=6 1.039 ± 0.184 4.75E-05 84,715 ± 68,312 0.002 Synthes Corp; OSU Dept. of OrthopaedicsReferences:[1] Zdero R. J Biomech Eng 131, 094503, 2009 Keywords: biomaterial, mechanical property Conference: 10th World Biomaterials Congress, Montréal, Canada, 17 May - 22 May, 2016. Presentation Type: General Session Oral Topic: Biomaterials in musculoskeletal orthopeadics and tissues Citation: Baumann ME and Litsky AS (2016). Screw pull out under cyclic fatigue loading in synthetic, cadaveric, and canine bone. Front. Bioeng. Biotechnol. Conference Abstract: 10th World Biomaterials Congress. doi: 10.3389/conf.FBIOE.2016.01.02084 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 27 Mar 2016; Published Online: 30 Mar 2016. * Correspondence: Dr. Alan S Litsky, Ohio State University, Biomedical Engineering, Columbus, OH, United States, litsky.1@osu.edu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Molly E Baumann Alan S Litsky Google Molly E Baumann Alan S Litsky Google Scholar Molly E Baumann Alan S Litsky PubMed Molly E Baumann Alan S Litsky Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page." @default.
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• W2319325618 title "Screw pull out under cyclic fatigue loading in synthetic, cadaveric, and canine bone" @default.
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