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- W2319325914 abstract "In an attempt to determine whether cate-cholamines serve a permissive role for the steroidogenic action of adrenocorticotrophic hormone (ACTH) in the adrenal cortex, as has been reported for the lipolytic action of ACTH on the fat pad(l), adrenals from re-serpine-treated rats were compared to glands from untreated rats with respect to their re-sponsivity in vitro to steroidogenic agents. No evidence for a permissive role for catechola-mines was obtained in the adrenal system, even when glands from resperine-treated rats were preincubated with acetylcholine and re-serpine in an attempt further to deplete residual catecholamines from the adrenals(2).However, an interesting difference in response to in vitro stimulation by ACTH, cyclic 3′,5′-adenosine monophosphate (3′,5′-AMP) or reduced triphosphopyridine nucleo-tide (NADPH) was shown by adrenals from reserpine-treated rats compared to those from untreated rats. The adrenals of the former group showed a considerably greater production of corticosteroids tha..." @default.
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- W2319325914 date "1964-02-01" @default.
- W2319325914 modified "2023-09-25" @default.
- W2319325914 title "Increased Responsivity of Adrenals from Reserpine-Treated or Stressed Rats to Steroidogenic Activity of AGTH" @default.
- W2319325914 doi "https://doi.org/10.3181/00379727-115-28894" @default.
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