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- W2319394420 abstract "Platelet function and serum lipoproteins were studied in patients with hypothyroidism. Platelet aggregation and ATP release were measured by Lumi-aggregometer using ADP, collagen and epinephrine as stimulants. Platelet factor 4 (PF4) and thromboxane B2 (TXB2) were determined by radioimmunoassay. High density lipoprotein (HDL) subfractions were determined by gradient gel electrophoresis. Apolipoproteins were measured by single radial immunodiffusion.Platelet aggregation increased in those patients at stimulating by epinephrine. ATP release also increased at stimulating by epinephrine. PF4 increased at stimulating by epinephrine, too. TXB2 increased at stimulating by ADP or epinephrine.Platelet aggregation was not correlated with thyroid hormone or total cholesterol or triglyceride. But it had a positive correlation tendency with HDL-cholesterol (HDL-C) or HDL2-C and a negative one with HDL3-C.These results suggested some relationship between platelet and HDL in patients with hypothyroidism." @default.
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- W2319394420 date "1987-01-01" @default.
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- W2319394420 title "Platelet function and lipoproteins in patients with hypothyroidism." @default.
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- W2319394420 doi "https://doi.org/10.2491/jjsth1970.18.145" @default.
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