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- W2319418354 abstract "<h3>Background</h3> Spirometry and biomarkers such as immunoglobulin E (IgE) levels, fractional exhaled nitric oxide concentration (FeNO) have been proposed for assessing the risk of future adverse events in Expert Panel Report 3 (US National Asthma Education and Prevention Program). <h3>Objectives</h3> Evaluating the interrelationship between spirometry parameters and/or biomarkers levels (IgE, FeNO, blood eosinophils percentage) and specific symptoms in asthmatic children between hospitalization episodes. <h3>Material and Methods</h3> 40 asthmatic pacients were evaluated performing spirometry and measuring biological parameters (Ig E levels, blood eosinophils, Fe NO). Symptoms like cough, dispnoea, wheezing described in patients diaries were analysed in correlation with the spirometric and biological parameters using t-Test, Mann-Whitney test, Pearson correlations. For each symptom analysed, every time two groups have emerged (with symptoms or without symptoms). <h3>Results</h3> Blood eosinophils were different for each symptom, p<0.05 comparing each time the groups. The tendency for positive corelations p=0.08 was noticed between FeNO and FEV1 (forced expiratory vital capacity). Positive corelations, p<0.05 were found between studied parameters, most of the time in the same group (either the group with symptoms or the group without symptoms). <h3>Conclusions</h3> Blood eosinophils and IgE levels may be regarded more as global predictors but FEV1 and FeNO may be considered more accurate predictors in risk assessment of future adverse events." @default.
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- W2319418354 date "2012-10-01" @default.
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- W2319418354 title "669 Monitoring the Asthmatic Children, A Prospective Study" @default.
- W2319418354 doi "https://doi.org/10.1136/archdischild-2012-302724.0669" @default.
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