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- W2319582518 abstract "Diamond nanoparticles (DNPs) obtained by explosive detonation have become commercially available. These commercial DNPs can be treated under Fenton conditions (FeSO4 and H2O2 at acidic pH) to obtain purer DNP samples with a small average particle size (4 nm) and a large population of surface OH groups (HO−DNPs). These Fenton-treated HO−DNPs have been used as a support of gold and platinum nanoparticles (≤2 nm average size). The resulting materials (Au/HO−DNP and Pt/HO−DNP) exhibit a high antioxidant activity against reactive oxygen species induced in a hepatoma cell line. In addition to presenting good biocompatibility, Au/HO− and Pt/HO−DNP exhibit about a two-fold higher antioxidant activity than glutathione, one of the reference antioxidant systems. The most active material against cellular oxidative stress was Au/HO−DNP." @default.
- W2319582518 created "2016-06-24" @default.
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- W2319582518 date "2010-10-12" @default.
- W2319582518 modified "2023-10-17" @default.
- W2319582518 title "Nano-Jewels in Biology. Gold and Platinum on Diamond Nanoparticles as Antioxidant Systems Against Cellular Oxidative Stress" @default.
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- W2319582518 doi "https://doi.org/10.1021/nn1019412" @default.
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