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- W2319661161 abstract "<h3>Background</h3> Bone loss in patients (pts) with early axial spondyloarthritis is insufficiently studied. <h3>Objectives</h3> To examine bone mineral density (BMD) at the femoral neck (FN) and lumbar spine (LS) in pts with early axial spondyloarthritis (axSpA). <h3>Methods</h3> 73 pts (33 men and 40 women) with early axSpA were included in this study; mean disease duration 19.9±14.4 months. Pts fulfilled ASAS criteria. Mean age 28.3±6.4 years, mean BASDAI 4.1±1.9; mean ASDAS-CRP 2.7±1.3. Clinical data were collected and BMD was measured using dual energy x-ray absorptiometry (DXA) of the FN and LS (L2–4). Low BMD was defined as T score ≤ -1. <h3>Results</h3> In all 73 pts mean T-score was -0.7±0.78 for the FN and -0.9±1.03 for the LS. In the group of pts with bone loss the BMD values were the following: mean T-score for the FN -1.5±0.39 and for the LS -1.6±0.46. Correlation has been detected between BMD reduction in the FN and in the LS (r =0.42; p=0.0001). The reduction in BMD was found in 44 (60.3%) pts. 27 (37.0%) pts had bone loss of the FN, 37 (50.7%) pts had bone loss of the LS, BMD reduction in both areas was found in 20 (27.4%) pts. <h3>Conclusions</h3> Systemic bone loss starts early in the disease process and is revealed in a considerable part of pts with early axSpA. This emphasizes the need for early intervention in axSpA. There is an association between low BMD in the FN and in the LS. <h3>Disclosure of Interest</h3> None declared <h3>DOI</h3> 10.1136/annrheumdis-2014-eular.3083" @default.
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- W2319661161 date "2014-06-01" @default.
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- W2319661161 title "AB0690 Bone Mineral Density in Patients with Early Axial Spondyloarthritis" @default.
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