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- W2319768905 abstract "In this research, the gas-phase stabilities of matched and mismatched duplex DNA were investigated by electrospray ionization-mass spectrometry (ESI-MS). The wild-type p53 duplex DNA [ds1, perfectly-matched (PM) DNA] was successfully distinguished from its three mutated DNAs [double-base mismatched DNA (DM)]. Moreover, the three DM DNAs were also well discriminated from each other using ESI-MS. Results show that the gas-phase thermodynamic stability of the DM DNAs decreased as the two mismatch spots moved closer. This implies that the dissociation of DM duplexes into two single strands prefers the mode “from middle to terminals”." @default.
- W2319768905 created "2016-06-24" @default.
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- W2319768905 date "2011-02-01" @default.
- W2319768905 modified "2023-10-16" @default.
- W2319768905 title "Investigation of Matched and Mismatched Duplex DNA by Electrospray Ionization-Mass Spectrometry" @default.
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- W2319768905 doi "https://doi.org/10.1255/ejms.1108" @default.
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