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• W2319974019 abstract "A revival of interest in protozoan immunology is urged. The discussion is based on intracellular parasites with emphasis on the antigens involved and their availability to host action, the influence of the stage of the parasite, the role of the host cell, the effects of the intracellular position, and the time relationships between parasite and host response mechanisms. Not an inclusive review; the coccidia, malaria parasites, and leishmania are given special consideration. I want first to thank Dr. von Brand for the warmth of his introduction. Next, I would acknowledge with sincere thanks my indebtedness to the members of the Society for the way in which they have honored me, and to the officers, the members of council, and committees for the enormous amount of work they do for the Society. Of this work I have been the largest beneficiary. We must continually reassess the status of a field. At first glance how crude the earlier day appears! But on deeper study, we learn that our own progress is not nearly so great as we at first thought. Often we forget the significance of earlier experiments and feel the need to repeat the work before reaching our own conviction in the matter. Hirst's recent review (1959) on Metchnikoff is an excellent example. I believe this is the time for reviving interest in in vivo studies of protozoan immunology. Much excellent work has already been done. However, it is my conviction that immunology has important contributions yet to make. And the fact that two sessions on the program of this meeting are devoted to immunology supports this view. In the final stages of man's conquest of his parasitic enemies, insecticide and behavioral resistance have arisen among the arthropod vectors, and new observations on drug resistance among the parasites themselves have been reported. Vector control and the search for new chemotherapeutic compounds must continue, but for the final stages of eradication of both human and animal infections, I believe immunology has yet to make its most important contributions. Zoonotic infections in animals in the wild may be difficult to eliminate and so constitute a threat to persons living in the area. Visceral leishmaniasis in East Africa is an example (Heyneman, 1961). However, I do not mean to stress only those infections with direct human implication, for trypanosomes and coccidia are examples of protozoan infections of animals of great economic importance. The fact that the Glasgow group of Jarrett, Jennings, McIntyre, Mulligan, Urquhart (1959), and their associates have been so successful in developing a live vaccine for a nematode infec* Presidential address, American Society of Parasitologists, Friday, 15 June 1962, 11:00 AM, State Room, Mayflower Hotel, Washington, D. C." @default.
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• W2319974019 date "1963-02-01" @default.
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• W2319974019 title "Some Aspects of Immunity to Intracellular Protozoan Parasites" @default.
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• W2319974019 doi "https://doi.org/10.2307/3275662" @default.
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