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- W2320008528 abstract "The cell, which is a fundamental unit of the life, has been constructed of biomembranes. The inside of the cell in which the complicated chemical reaction progresses has been divided three-dimensionally by the biomembranes which are mainly composed of proteins and lipids. The function appears on membrane protein by the interaction with the lipid and is affected by the physical property of membrane lipid. In the cell, various biological phenomena occur in the regions divided by the biomembranes. Image analysis system under the microscope makes it possible to obtain spatial and time-related information of the biological phenomena in order to clarify the biological system of cell. We have developed the equipment that images the physical property of the biomembrane at video rate under the microscope using fluorescence dye Laurdan. This equipment was applied to the analysis of the fluidity change of the cell membrane of PC12 cell in the apoptosis process. And, it was applied to Giant liposome prepared for bilayer mixture of DMPC and DMPE, and the phase separation phenomenon was observed at the video rate." @default.
- W2320008528 created "2016-06-24" @default.
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- W2320008528 date "2002-01-01" @default.
- W2320008528 modified "2023-10-01" @default.
- W2320008528 title "Regulation of Biomembrane Function by Physical Properties of The Membrane: Methodological Change from 'To Measure' to 'To See'." @default.
- W2320008528 doi "https://doi.org/10.5360/membrane.27.164" @default.
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