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- W2320043764 abstract "The aim of study was to correlate the bronchoalveolar lavage (BAL) cell subpopulations in light microscopy and clinical-functional parameters in 20 children with chronic nonproductive cough (potentially evolving to asthma) in comparison with 20 children with mild and moderate stable asthma. The results revealed a different BAL cell profile of chronic coughing children, characterized by a lower percent of total cells (0.279 +/- 0.055 x 10(6)/ml), eosinophils (0.97 +/- 0.80%), lymphocytes (6.02 +/- 0.85%) and epithelial cells (28.52 +/- 5.15%) and higher percent of macrophages (46.05 +/- 7.94%) and neutrophils (18.27 +/- 4.93%). Eosinophilic inflammation in BAL and bronchial hyper-responsiveness (PC20 methacholine = 1.73 +/- 0.15 mg/ml) were revealed in three cases with chronic cough. Based on these reasons, they were included in cough variant asthma. In conclusion, children with nonproductive chronic cough represent a heterogenous group, with different underlying causes. Only a minority of these patients has cough variant asthma, with a favorable response to inhaled corticotherapy." @default.
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- W2320043764 date "2004-01-02" @default.
- W2320043764 modified "2023-10-17" @default.
- W2320043764 title "[Characteristics of bronchial inflammation in children with chronic non-productive cough]." @default.
- W2320043764 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14702696" @default.
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