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- W2320058962 abstract "Gleason gradinge system remains the most widely used system and one of the most useful predictors of prognosis of prostate cancer. Donald F. Gleason in 1966 created a unique grading system for prostatic carcinoma based solely on the architectural pattern. Five distinct architectural patterns are identified, being 1 most differentiated and 5 least differentiated. first after the declaration, the serum prostate specific antigen (PSA) began to be widely used,with numerous examples 18g needle in needle biopsies made, it is noted in radical prostatectomy (RP) multiple tumor nodules, and basal cells shown immunohistochemically, adenocarcinoma of the prostate to treatment, such as radiotherapy and chemotherapy was added and new variants were defined. After all these developments the International Society of Urological Pathology (ISUP) introduced major modifications to the Gleason system in 2005. Subsequent proposals for slight modifications of the ISUP grading system are were declared by the ISUP in 2010. Gleason score 2-4 is markedly reduced over the years. Helpap and Egevad (1) demonstrated Gleason score 5 on biopsy, which would encompass 2+3=5 or 3+2=5, also decreased from 12.2% Dr. Lutfi Kirdar Kartal Training and Research Hospital, Clinic of Pathology, Istanbul, Turkey Prostat Karsinomunda Gleason Dereceleme Sisteminin Yeni Degerlemesi" @default.
- W2320058962 created "2016-06-24" @default.
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- W2320058962 date "2016-03-30" @default.
- W2320058962 modified "2023-09-25" @default.
- W2320058962 title "New Assessment of Gleason Grading System in Prostatic Adenocarcinoma" @default.
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- W2320058962 doi "https://doi.org/10.4274/jus.796" @default.
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