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- W2320124223 abstract "An external pinkish growing mass that emerged from the right nostril of an adult goldfish Carassius auratus L. was evaluated by means of light microscopy and immunohistochemistry. The neoplasm presented a well-developed fibrovascular stroma associated with solid cell nests and a large number of Flexner-Wintersteiner rosettes. Myelinated fibres were observed around them. Neoplastic cells showed a prominent degree of nuclear atypia and low mitotic activity. The latter was in agreement with the low reactivity of tumour cells to anti-proliferating cell nuclear antigen antibody. Immunohistochemistry also revealed anti-neuronal nitric oxide synthase, anti-S100 protein, antineuropeptide Y, and anti-cytokeratin immunoreactivity in tumour cells as well as in normal olfactory epithelium of goldfish control sections. Histopathological and immunohistochemical findings strongly suggest a diagnosis of an olfactory neuroblastoma (ONB). To our knowledge this is the first description of ONB in goldfish." @default.
- W2320124223 created "2016-06-24" @default.
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- W2320124223 date "2011-08-29" @default.
- W2320124223 modified "2023-09-26" @default.
- W2320124223 title "First description of an olfactory neuroblastoma in goldfish Carassius auratus: a case report" @default.
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- W2320124223 doi "https://doi.org/10.3354/dao02383" @default.
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