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- W2320153171 abstract "Greater comorbidity burden is correlated with poor patient outcomes among individuals with diabetes, but which condition clusters are most prevalent remains unclear. By identifying the most common multiple chronic condition (MCC) patterns, this study could help prioritize comorbidities to be addressed by clinical guidelines. We conducted cross-sectional analysis of the 2008-2012 Humedica dataset containing information from electronic health records, encounter data, and lab values supplied by provider networks across the U.S. Our cohort included adults (aged ≥18 years) with type 2 diabetes and at least 24 months of ambulatory and hospital data (n=162,332). Of the 14 comorbidities listed in the 2012 American Diabetes Association guidelines, we selected the eight conditions that each affected ≥10% of the patients and analyzed the most common patterns of MCCs by age group. 89.1% of diabetes patients had at least one comorbidity and 40.9% had three or more. Conditions with a prevalence rate ≥10% included hypertension (74.7%), hyperlipidemia (65.8%), coronary artery disease (CAD, 17.7%), cancers (17.1%), COPD/asthma (14.2%), arthritis (14.0%), chronic kidney disease (CKD, 12.0%), and depression (11.4%). The leading combination was hypertension and hyperlipidemia only, accounting for 21.1% of the population, followed by hypertension only (10.9%), hyperlipidemia only (5.0%), and the combination of hypertension and hyperlipidemia plus CAD (4.7%). Older adults (≥65 years) were more likely than younger adults (<65 years) to have all comorbidities except depression (7.6% vs. 10.1%, p= <0.0001), though the condition rankings were similar in both groups. Diabetes patients have substantial comorbidities but the patterns vary considerably across patients. Although most diabetes guidelines address co-management of hypertension and hyperlipidemia, this MCC subgroup accounts for only one-fifth of patients. The development of evidence-based strategies to manage MCCs would help physicians and patients prioritize therapies and goals." @default.
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- W2320153171 date "2013-05-01" @default.
- W2320153171 modified "2023-09-25" @default.
- W2320153171 title "Patterns Of Comorbidity Clusters Among Adults With Diabetes" @default.
- W2320153171 doi "https://doi.org/10.1016/j.jval.2013.03.774" @default.
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