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• W2320176952 abstract "From a systematic investigation involving the synthesis of a series of catalysts and screening studies, the organocatalyst 16, which is sterically hindered, contains a strong hydrogen-bonding site, and is endowed with reinforced chirality, is shown to promote the Biginelli cyclocondensation of aromatic as well as aliphatic aldehydes with ethyl acetoacetate and urea in a remarkably high enantioselectivity (ee ca. 94-99%)." @default.
• W2320176952 created "2016-06-24" @default.
• W2320176952 creator A5017175293 @default.
• W2320176952 creator A5081564628 @default.
• W2320176952 date "2010-12-30" @default.
• W2320176952 modified "2023-09-30" @default.
• W2320176952 title "Enantioselective Organocatalytic Biginelli Reaction: Dependence of the Catalyst on Sterics, Hydrogen Bonding, and Reinforced Chirality" @default.
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• W2320176952 doi "https://doi.org/10.1021/jo101717m" @default.
• W2320176952 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21192642" @default.
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