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- W2320207007 abstract "We determined the proportions of matched kidney transplant isotope GFRs (iGFRs) to the estimated functions (eGFRs) calculated from Isotope Dilution Mass Spectrometry (IDMS), Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), and Cockcroft-Gault (CG) equations. One thousand four hundred and three iGFR/eGFR pairs on 390 kidney transplant patients were compared considering the iGFR or eGFR as the reference or test variable. Conformity of iGFR to CG estimates demonstrated the least bias of 1.3±18.4 mL/min/1.73 m 2 (compared to 1.5±19.4 and - 2.2±19.2 for IDMS and CKDI-EPI, P<0.05) and CKD-EPI estimates the highest precision of 4.1±41.8 (compared to 11.3±43.9 for IDMS and 5.7±37.3 for CG; P<0.05). IDMS eGFR cut off less than 60 and less than 30 mL/min/1.73m 2 were correctly matched by iGFR in 79.4% and 49.1% of the times, while CKD-EPI was matched by iGFR in 83.5% and 52.5%. CG was matched in 78.3% and 53.6%. IGFR cut off levels of less than 60, and less than 30 mL/min/1.73m 2 were predicted by IDMS in 83.8% and 64.0% of the times. CKD-EPI was correct in 77.8% and 59.0% and CG in 82.5% and 41.6%, respectively. Transplant eGFR results obtained by CKD-EPI or CG are likely to be more precise and less biased than IDMS." @default.
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- W2320207007 date "2011-01-01" @default.
- W2320207007 modified "2023-10-06" @default.
- W2320207007 title "The Practical Implications of Using Estimated GFR as the Presumed Reference Variable to Estimate Transplant Chronic Kidney Disease" @default.
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- W2320207007 doi "https://doi.org/10.4081/nr.2011.e2" @default.
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