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- W2320235553 abstract "The purpose of this study is to investigate the alcohol preference in rats and to determine the utility of a new method; Alc-Alc two-bottle method.Ss were 8 male albino rats 100 days old in Exp. I, and 11 male albino rats 75 days old in Exp. II. They were given access to 2 alcohol solutions of different concentrations, and the amount of each fluid consumed during a period of 24 hours was recorded. In a session of 8 days, such procedure was repeated on alternate days to control the effects of position and bottle. On non-test days water was available in the 2 drinking spouts. This test was conducted over every combination of 2 in 4 concentrations : 3, 5, 7, and 9 (vol. %). Test sequences were as follows : 3-5, 5-7, 7-9, 3-7, 5-9, 3-9, in Exp. I; 3-9, 5-9, 3-7, 7-9, 5-7, 3-5, 3-9, 5-9, 3-7, in Exp. II.The main results : i) 3 types of preference were observed in the range of 3% to 9 %, the higher concentration preference, the lower concentration preference, and the middle concentration preference (See Fig. 1, Fig. 5 and Table 1). A greater difference in the concentration of a pair of the solutions tends to clearly reveal the type of preference (See Fig. 2 and Fig. 4). ii) The lower concentration preference observed here was considered to be confounded with alcohol rejection (See Fig. 3 and Fig. 6). iii) All rats rejected alcohol in the first session, and some of them turned to select the higher concentrations after a few sessions (See Fig. 4 and Fig. 6). iv) The patterns of selection in every pair of solutions were transitional to each other in most rats (See Table 1)." @default.
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- W2320235553 date "1973-01-01" @default.
- W2320235553 modified "2023-09-24" @default.
- W2320235553 title "An Analysis of Alcohol Preference in Rats with Alcohol vs. Alcohol Two-Bottle Method" @default.
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- W2320235553 doi "https://doi.org/10.2502/janip1944.23.15" @default.
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