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- W2320301001 abstract "術中の麻酔維持に持続硬膜外麻酔を用いた小児32例において,術後硬膜外鎮痛を行ない,メピバカインの血中濃度を測定した.術後鎮痛には,1%メピバカインを0.2ml/kg/hr(最大8ml/hr)の速度で投与し,投与開始後0時間,6時間,18時間,24時間,48時間に採血した.各時間におけるメピバカインの血中濃度は,投与開始後0時間値は3.2±0.9μ/ml (n=32),開始後6時間値は2.0±0.6μg/ml (n=22)で前値に比し有意に低下した.その後次第に上昇し,開始後18時間値は2.4±0.5μg/ml (n=23),開始後24時間値は2.6±1.3μg/ml (n=9),開始後48時間値は2.7±1.5μg/ml (n=7)であったが,全経過中,中毒閾値に達した症例はなかった." @default.
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- W2320301001 date "1998-01-01" @default.
- W2320301001 modified "2023-10-02" @default.
- W2320301001 title "Plasma Concentration of Mepivacaine in Pediatric Patients with Postoperative-epidural Analgesia." @default.
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- W2320301001 doi "https://doi.org/10.2199/jjsca.18.375" @default.
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