Matches in SemOpenAlex for { <https://semopenalex.org/work/W2320327400> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2320327400 endingPage "80" @default.
- W2320327400 startingPage "73" @default.
- W2320327400 abstract "Conformations of the catalytic center of protein tyrosine phosphatase 1B (PTP1B) and surrounding loops are known to be important in catalysis and inhibition of the enzyme. There were 98 conformations from 88 PDB files representing PTP1B with different ligands which were analyzed to investigate the details of loop 110-120 movement and mobility of separate residues. The differences were identified by a special software tool which performs multiple comparisons of selected parts of PDB files. The conformations were divided into 6 clusters. It was found that the loop formed by residues 110-120 can be characterized by four main conformations. Predominantly, the loop 110-120 adopts the main conformation and keeps it during WPD loop movement. Three other conformations appear to be stabilized in case of closed WPD loop and seem to be favorable for PTP1B with subunit structure." @default.
- W2320327400 created "2016-06-24" @default.
- W2320327400 creator A5058330710 @default.
- W2320327400 creator A5063612945 @default.
- W2320327400 creator A5072880241 @default.
- W2320327400 date "2013-10-28" @default.
- W2320327400 modified "2023-09-27" @default.
- W2320327400 title "Analysis of conformational flexibility of loop 110-120 of protein tyrosine phosphatase 1B" @default.
- W2320327400 cites W1592311769 @default.
- W2320327400 cites W1820879344 @default.
- W2320327400 cites W1964974170 @default.
- W2320327400 cites W1966041739 @default.
- W2320327400 cites W1980100825 @default.
- W2320327400 cites W1980586346 @default.
- W2320327400 cites W1983555000 @default.
- W2320327400 cites W2015642465 @default.
- W2320327400 cites W2033921253 @default.
- W2320327400 cites W2043617798 @default.
- W2320327400 cites W2046840022 @default.
- W2320327400 cites W2047038656 @default.
- W2320327400 cites W2058315465 @default.
- W2320327400 cites W2061594512 @default.
- W2320327400 cites W2062539991 @default.
- W2320327400 cites W2076531166 @default.
- W2320327400 cites W2081912151 @default.
- W2320327400 cites W2083749076 @default.
- W2320327400 cites W2107995523 @default.
- W2320327400 cites W2124876030 @default.
- W2320327400 cites W2141911861 @default.
- W2320327400 cites W2144146259 @default.
- W2320327400 doi "https://doi.org/10.15407/ubj85.05.073" @default.
- W2320327400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24479324" @default.
- W2320327400 hasPublicationYear "2013" @default.
- W2320327400 type Work @default.
- W2320327400 sameAs 2320327400 @default.
- W2320327400 citedByCount "0" @default.
- W2320327400 crossrefType "journal-article" @default.
- W2320327400 hasAuthorship W2320327400A5058330710 @default.
- W2320327400 hasAuthorship W2320327400A5063612945 @default.
- W2320327400 hasAuthorship W2320327400A5072880241 @default.
- W2320327400 hasBestOaLocation W23203274001 @default.
- W2320327400 hasConcept C104292427 @default.
- W2320327400 hasConcept C104317684 @default.
- W2320327400 hasConcept C105795698 @default.
- W2320327400 hasConcept C114614502 @default.
- W2320327400 hasConcept C178666793 @default.
- W2320327400 hasConcept C181199279 @default.
- W2320327400 hasConcept C184670325 @default.
- W2320327400 hasConcept C185592680 @default.
- W2320327400 hasConcept C2776165026 @default.
- W2320327400 hasConcept C2777936996 @default.
- W2320327400 hasConcept C2780598303 @default.
- W2320327400 hasConcept C33923547 @default.
- W2320327400 hasConcept C47701112 @default.
- W2320327400 hasConcept C55493867 @default.
- W2320327400 hasConcept C65556437 @default.
- W2320327400 hasConcept C71240020 @default.
- W2320327400 hasConcept C8010536 @default.
- W2320327400 hasConcept C85528070 @default.
- W2320327400 hasConceptScore W2320327400C104292427 @default.
- W2320327400 hasConceptScore W2320327400C104317684 @default.
- W2320327400 hasConceptScore W2320327400C105795698 @default.
- W2320327400 hasConceptScore W2320327400C114614502 @default.
- W2320327400 hasConceptScore W2320327400C178666793 @default.
- W2320327400 hasConceptScore W2320327400C181199279 @default.
- W2320327400 hasConceptScore W2320327400C184670325 @default.
- W2320327400 hasConceptScore W2320327400C185592680 @default.
- W2320327400 hasConceptScore W2320327400C2776165026 @default.
- W2320327400 hasConceptScore W2320327400C2777936996 @default.
- W2320327400 hasConceptScore W2320327400C2780598303 @default.
- W2320327400 hasConceptScore W2320327400C33923547 @default.
- W2320327400 hasConceptScore W2320327400C47701112 @default.
- W2320327400 hasConceptScore W2320327400C55493867 @default.
- W2320327400 hasConceptScore W2320327400C65556437 @default.
- W2320327400 hasConceptScore W2320327400C71240020 @default.
- W2320327400 hasConceptScore W2320327400C8010536 @default.
- W2320327400 hasConceptScore W2320327400C85528070 @default.
- W2320327400 hasIssue "6" @default.
- W2320327400 hasLocation W23203274001 @default.
- W2320327400 hasLocation W23203274002 @default.
- W2320327400 hasOpenAccess W2320327400 @default.
- W2320327400 hasPrimaryLocation W23203274001 @default.
- W2320327400 hasRelatedWork W1593725015 @default.
- W2320327400 hasRelatedWork W1968905431 @default.
- W2320327400 hasRelatedWork W1974312557 @default.
- W2320327400 hasRelatedWork W1979034912 @default.
- W2320327400 hasRelatedWork W2011394755 @default.
- W2320327400 hasRelatedWork W2131922759 @default.
- W2320327400 hasRelatedWork W2320327400 @default.
- W2320327400 hasRelatedWork W2391335135 @default.
- W2320327400 hasRelatedWork W2776422916 @default.
- W2320327400 hasRelatedWork W4309066007 @default.
- W2320327400 hasVolume "85" @default.
- W2320327400 isParatext "false" @default.
- W2320327400 isRetracted "false" @default.
- W2320327400 magId "2320327400" @default.
- W2320327400 workType "article" @default.