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- W2320463312 endingPage "14219" @default.
- W2320463312 startingPage "14219" @default.
- W2320463312 abstract "Non-alcoholic fatty liver disease (NAFLD) is an umbrella term to describe the entire spectrum of this common liver disease. In patients with NAFLD, especially those with non-alcoholic steatohepatitis (NASH), most often have one or more components of the metabolic syndrome, but this is not universal. Although most patients with NAFLD share many clinical features, only a subset of patients develops significant liver inflammation and progressive fibrosis. On the other hand, not all patients with NASH exhibit insulin resistance. NASH can be seen in patients who are lean and have no identifiable risk factors. Many clinical studies have tried numerous drugs and alternative medicine, however, investigators have failed to identify a safe and effective therapy for patients with NASH. As summarized, the heterogeneity of pathogenic pathways in individual patients with NASH may warrant the development of an individualized treatment according to the underlying pathogenic pathway. The differentiation of pathogenetic targets may require the development of diagnostic and prognostic biomarkers, and the identification of genetic susceptibilities. At present, evidence-based medicine provides only a few options including life-style modifications targeting weight loss, pioglitazone and vitamin E in non-diabetic patients with biopsy-proven NASH." @default.
- W2320463312 created "2016-06-24" @default.
- W2320463312 creator A5027003965 @default.
- W2320463312 creator A5031566074 @default.
- W2320463312 date "2014-01-01" @default.
- W2320463312 modified "2023-10-16" @default.
- W2320463312 title "Non-alcoholic fatty liver disease: What has changed in the treatment since the beginning?" @default.
- W2320463312 cites W1534242660 @default.
- W2320463312 cites W1622799587 @default.
- W2320463312 cites W177929472 @default.
- W2320463312 cites W1784461125 @default.
- W2320463312 cites W1852074853 @default.
- W2320463312 cites W1868475579 @default.
- W2320463312 cites W191621842 @default.
- W2320463312 cites W1922087192 @default.
- W2320463312 cites W1964375545 @default.
- W2320463312 cites W1965367230 @default.
- W2320463312 cites W1967932879 @default.
- W2320463312 cites W1967972402 @default.
- W2320463312 cites W1968304503 @default.
- W2320463312 cites W1969295126 @default.
- W2320463312 cites W1972866300 @default.
- W2320463312 cites W1975691929 @default.
- W2320463312 cites W1978128204 @default.
- W2320463312 cites W1983417944 @default.
- W2320463312 cites W1985592156 @default.
- W2320463312 cites W1990055069 @default.
- W2320463312 cites W1990168800 @default.
- W2320463312 cites W1991061893 @default.
- W2320463312 cites W1993918101 @default.
- W2320463312 cites W1996266503 @default.
- W2320463312 cites W1999225509 @default.
- W2320463312 cites W2006999442 @default.
- W2320463312 cites W2010662354 @default.
- W2320463312 cites W2012189675 @default.
- W2320463312 cites W2019071303 @default.
- W2320463312 cites W2019280401 @default.
- W2320463312 cites W2023210973 @default.
- W2320463312 cites W2026304182 @default.
- W2320463312 cites W2027360957 @default.
- W2320463312 cites W2030739359 @default.
- W2320463312 cites W2032486106 @default.
- W2320463312 cites W2034700421 @default.
- W2320463312 cites W2042152924 @default.
- W2320463312 cites W2044136402 @default.
- W2320463312 cites W2053210088 @default.
- W2320463312 cites W2053295375 @default.
- W2320463312 cites W2059196301 @default.
- W2320463312 cites W2061363337 @default.
- W2320463312 cites W2062812115 @default.
- W2320463312 cites W2071539877 @default.
- W2320463312 cites W2073171519 @default.
- W2320463312 cites W2076204761 @default.
- W2320463312 cites W2077071754 @default.
- W2320463312 cites W2086200071 @default.
- W2320463312 cites W2086400441 @default.
- W2320463312 cites W2089342771 @default.
- W2320463312 cites W2091876682 @default.
- W2320463312 cites W2097677758 @default.
- W2320463312 cites W2098689751 @default.
- W2320463312 cites W2098730220 @default.
- W2320463312 cites W2102656403 @default.
- W2320463312 cites W2103156933 @default.
- W2320463312 cites W2106061083 @default.
- W2320463312 cites W2107732097 @default.
- W2320463312 cites W2109331941 @default.
- W2320463312 cites W2114090706 @default.
- W2320463312 cites W2116393673 @default.
- W2320463312 cites W2120397203 @default.
- W2320463312 cites W2122904762 @default.
- W2320463312 cites W2131133480 @default.
- W2320463312 cites W2132520424 @default.
- W2320463312 cites W2133750777 @default.
- W2320463312 cites W2135788465 @default.
- W2320463312 cites W2136226749 @default.
- W2320463312 cites W2139112405 @default.
- W2320463312 cites W2139252205 @default.
- W2320463312 cites W2140068099 @default.
- W2320463312 cites W2141920115 @default.
- W2320463312 cites W2144178804 @default.
- W2320463312 cites W2147617075 @default.
- W2320463312 cites W2154075360 @default.
- W2320463312 cites W2155259249 @default.
- W2320463312 cites W2155384570 @default.
- W2320463312 cites W2155814388 @default.
- W2320463312 cites W2157162247 @default.
- W2320463312 cites W2157671355 @default.
- W2320463312 cites W2159686760 @default.
- W2320463312 cites W2160887608 @default.
- W2320463312 cites W2161526491 @default.
- W2320463312 cites W2162051951 @default.
- W2320463312 cites W2164118055 @default.
- W2320463312 cites W2316193238 @default.
- W2320463312 cites W2330060845 @default.
- W2320463312 cites W4252226584 @default.
- W2320463312 cites W4376849750 @default.
- W2320463312 doi "https://doi.org/10.3748/wjg.v20.i39.14219" @default.
- W2320463312 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4202350" @default.