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- W2320602119 abstract "57歳女性。初診の約2年前に左踵内側の褐色局面に気付いた。以後大きさ, 色調に変化はなかった。当科初診時, 同部に8.9×11.9×1.0mm大の, 淡褐色～褐色の扁平隆起性局面を認めた。全摘して組織学的に検討した。表皮には基底層部にメラノサイトの軽度の増数が見出され, 真皮浅層には顕著な線維化層が広範に認められた。この線維化層の下の真皮中深層部に異型細胞の増殖巣が見出され, 免疫染色にてS-100, MART-1陽性, HMB45陰性であった。組織学的に診断困難であったが, 悪性黒色腫を否定できないと考え, 原発巣の拡大再切除とセンチネルリンパ節生検を施行した。センチネルリンパ節の実質辺縁部にMART-1とHMB45陽性の細胞が数個散在性に見出された。本症例を悪性黒色腫と考え, 原発切除創周囲にインターフェロンβ蛋白の局注を施行している。" @default.
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- W2320602119 date "2006-01-01" @default.
- W2320602119 modified "2023-10-14" @default.
- W2320602119 title "A case of malignant melanoma with confusing histopathological features in the primary lesion" @default.
- W2320602119 doi "https://doi.org/10.5227/skincancer.21.31" @default.
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