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W2320619100 abstract "The design of immunogens for raising antisera containing antibodies specifically directed against paracetamol is discussed. A derivative of the drug with minimal structural alteration was synthesised, coupled to the carrier protein key-hole limpet haemocyanin, and used to immunise sheep. The evaluation of the resulting antisera is described. Preparation of a fluorescent label with reduced bridge-binding then allowed the development of a polarisation fluoroimmunoassay for paracetamol in buffer, suitable for conversion to a direct serum assay." @default.
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W2320619100 date "1988-01-01" @default.
W2320619100 modified "2023-09-26" @default.
W2320619100 title "Design of the Immunogen and Label for Use in a Fluoroimmunoassay for Paracetamol" @default.
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W2320619100 doi "https://doi.org/10.1177/000456328802500105" @default.
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