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- W2320785810 abstract "Absorption and excretion were investigated with healthy male volunteers dosed preprandial and post-prandial 3 times a day with equimolar dose of ampicillin and talampicillin.The results were shown that drug absorption was influenced by meal even on the groups of pre-prandial administration, and on post-prandial administered groups, the influences were more remarkable.On post-prandial administered cases, absorption of drug was prolonged and the peakof blood concentrations were lowered dose by dose.Blood concentrations after each medication of talampicillin were kept higher than twice or more that of ampicillin.Total urinary excretion rate after administration of talampicillin t. i. d. was shown about twice compaired with ampicillin medicated cases of either pre- or post-prandial administrations.Urinary concentration through night was highest in talampicillin post-prandial medicated group in comparison with other groups." @default.
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- W2320785810 date "1975-01-01" @default.
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- W2320785810 title "Studies on Talampicillin" @default.
- W2320785810 doi "https://doi.org/10.11150/kansenshogakuzasshi1970.49.458" @default.
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