Matches in SemOpenAlex for { <https://semopenalex.org/work/W2320797417> ?p ?o ?g. }
- W2320797417 endingPage "414" @default.
- W2320797417 startingPage "408" @default.
- W2320797417 abstract "Background— Abnormal microvolt T-wave alternans (MTWA), a marker of ventricular arrhythmic risk, is a highly prevalent condition in patients with type 2 diabetes mellitus (T2DM) and is correlated with glycemic control. However, there is uncertainty as to whether central or peripheral hemodynamic factors are associated with abnormal MTWA in T2DM individuals. Methods and Results— We studied 50 consecutive, well-controlled T2DM outpatients without a history of ischemic heart disease and with normal systolic function. All patients underwent a complete echocardiographic Doppler evaluation with spectral tissue Doppler analysis. MTWA analysis was performed noninvasively during submaximal exercise. Effective arterial elastance, arterial compliance, and heart rate variability were also measured. Compared with patients with MTWA negativity (n=38), those with MTWA abnormality (n=12, 24%) had significantly lower e′ (7.6±1.3 versus 9.1±1.7 cm/s; P <0.01), a′ (10.2±1.6 versus 12.7±1.9 cm/s; P <0.001) and s′ velocities (8.7±1.1 versus 10.2±1.5 cm/s; P =0.001) and higher indexed left ventricular mass (121.3±16.4 versus 107.5±16.5 g/m 2 ; P =0.016), indexed left atrial volume (33.5±11.9 versus 23.6±5.6 mL/m 2 ; P <0.001), and E/e′ ratio (8.8±1.4 versus 6.5±1.3; P <0.001). Multivariable logistic regression analysis revealed that higher E/e′ ratio was the only independent correlate of abnormal MTWA (adjusted odds ratio, 3.52; 95% confidence interval, 1.19 to 10.6; P =0.02) after controlling for glycemic control and other potential confounders. Conclusions— In this pilot study, we found that early diastolic dysfunction, as measured by tissue Doppler imaging, is independently associated with MTWA abnormality in T2DM individuals with normal systolic function. Further larger studies are needed to examine the reproducibility of these results." @default.
- W2320797417 created "2016-06-24" @default.
- W2320797417 creator A5001168456 @default.
- W2320797417 creator A5002148281 @default.
- W2320797417 creator A5033999060 @default.
- W2320797417 creator A5038898384 @default.
- W2320797417 creator A5044161688 @default.
- W2320797417 creator A5046442411 @default.
- W2320797417 creator A5048759251 @default.
- W2320797417 creator A5056782644 @default.
- W2320797417 creator A5071075382 @default.
- W2320797417 creator A5084120800 @default.
- W2320797417 date "2011-07-01" @default.
- W2320797417 modified "2023-09-26" @default.
- W2320797417 title "Relationship Between Early Diastolic Dysfunction and Abnormal Microvolt T-Wave Alternans in Patients With Type 2 Diabetes" @default.
- W2320797417 cites W1503470162 @default.
- W2320797417 cites W1597964526 @default.
- W2320797417 cites W1969298205 @default.
- W2320797417 cites W1971809538 @default.
- W2320797417 cites W1982883262 @default.
- W2320797417 cites W1983019374 @default.
- W2320797417 cites W1984623267 @default.
- W2320797417 cites W1987613101 @default.
- W2320797417 cites W1995612707 @default.
- W2320797417 cites W1995758408 @default.
- W2320797417 cites W1997183811 @default.
- W2320797417 cites W2009775227 @default.
- W2320797417 cites W2014328014 @default.
- W2320797417 cites W2025954605 @default.
- W2320797417 cites W2040932618 @default.
- W2320797417 cites W2048199961 @default.
- W2320797417 cites W2048728045 @default.
- W2320797417 cites W2056063595 @default.
- W2320797417 cites W2057396267 @default.
- W2320797417 cites W2059254718 @default.
- W2320797417 cites W2061973954 @default.
- W2320797417 cites W2074739150 @default.
- W2320797417 cites W2078310558 @default.
- W2320797417 cites W2086170960 @default.
- W2320797417 cites W2098623700 @default.
- W2320797417 cites W2101330115 @default.
- W2320797417 cites W2103183876 @default.
- W2320797417 cites W2119133252 @default.
- W2320797417 cites W2146578470 @default.
- W2320797417 cites W2158084840 @default.
- W2320797417 cites W2162718501 @default.
- W2320797417 cites W2165111060 @default.
- W2320797417 cites W2334859129 @default.
- W2320797417 cites W2615048085 @default.
- W2320797417 cites W72511963 @default.
- W2320797417 cites W84927980 @default.
- W2320797417 doi "https://doi.org/10.1161/circimaging.110.962951" @default.
- W2320797417 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21502332" @default.
- W2320797417 hasPublicationYear "2011" @default.
- W2320797417 type Work @default.
- W2320797417 sameAs 2320797417 @default.
- W2320797417 citedByCount "12" @default.
- W2320797417 countsByYear W23207974172012 @default.
- W2320797417 countsByYear W23207974172013 @default.
- W2320797417 countsByYear W23207974172015 @default.
- W2320797417 countsByYear W23207974172016 @default.
- W2320797417 countsByYear W23207974172017 @default.
- W2320797417 countsByYear W23207974172018 @default.
- W2320797417 crossrefType "journal-article" @default.
- W2320797417 hasAuthorship W2320797417A5001168456 @default.
- W2320797417 hasAuthorship W2320797417A5002148281 @default.
- W2320797417 hasAuthorship W2320797417A5033999060 @default.
- W2320797417 hasAuthorship W2320797417A5038898384 @default.
- W2320797417 hasAuthorship W2320797417A5044161688 @default.
- W2320797417 hasAuthorship W2320797417A5046442411 @default.
- W2320797417 hasAuthorship W2320797417A5048759251 @default.
- W2320797417 hasAuthorship W2320797417A5056782644 @default.
- W2320797417 hasAuthorship W2320797417A5071075382 @default.
- W2320797417 hasAuthorship W2320797417A5084120800 @default.
- W2320797417 hasBestOaLocation W23207974171 @default.
- W2320797417 hasConcept C126322002 @default.
- W2320797417 hasConcept C164705383 @default.
- W2320797417 hasConcept C178853913 @default.
- W2320797417 hasConcept C2775935837 @default.
- W2320797417 hasConcept C2777325121 @default.
- W2320797417 hasConcept C2778198053 @default.
- W2320797417 hasConcept C57900726 @default.
- W2320797417 hasConcept C71924100 @default.
- W2320797417 hasConcept C84393581 @default.
- W2320797417 hasConceptScore W2320797417C126322002 @default.
- W2320797417 hasConceptScore W2320797417C164705383 @default.
- W2320797417 hasConceptScore W2320797417C178853913 @default.
- W2320797417 hasConceptScore W2320797417C2775935837 @default.
- W2320797417 hasConceptScore W2320797417C2777325121 @default.
- W2320797417 hasConceptScore W2320797417C2778198053 @default.
- W2320797417 hasConceptScore W2320797417C57900726 @default.
- W2320797417 hasConceptScore W2320797417C71924100 @default.
- W2320797417 hasConceptScore W2320797417C84393581 @default.
- W2320797417 hasIssue "4" @default.
- W2320797417 hasLocation W23207974171 @default.
- W2320797417 hasLocation W23207974172 @default.
- W2320797417 hasOpenAccess W2320797417 @default.
- W2320797417 hasPrimaryLocation W23207974171 @default.